Odontogenic infections remain a significant clinical challenge in dental practice due to their potential for rapid progression and life-threatening complications. These infections originate from dental or periodontal tissues and may spread to adjacent fascial spaces if not managed appropriately.
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The management framework proposed by Peterson et al. continues to be widely accepted and serves as a systematic, evidence-based protocol for controlling odontogenic infections while minimizing morbidity and mortality.
✅ Conceptual Framework for the Management of Odontogenic Infections
Although Peterson et al. originally proposed an eight-step protocol for the management of odontogenic infections, Velasco and Soto later introduced a simplified and clinically oriented adaptation. In their article Principles for the Management of Odontogenic Infections with Different Levels of Complexity, the authors condensed the original framework into seven core principles, maintaining diagnostic rigor and therapeutic effectiveness while improving clinical applicability.
This simplified model emphasizes sound clinical decision-making, prioritization of surgical intervention, and patient-centered care, making it particularly valuable in routine dental practice and academic training. Accordingly, the present article adopts the seven-step protocol proposed by Velasco and Soto, which remains firmly grounded in Peterson’s original principles while offering a more streamlined and practical approach for managing odontogenic infections across varying levels of severity.
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PDF 🔽 Odontogenic facial cellulitis in a pediatric patient - Diagnosis, treatment and multidisciplinary management ... Odontogenic facial cellulitis in pediatric patients represents a potentially serious complication of untreated dental infections, characterized by the rapid spread of bacteria through facial and cervical soft tissues.I. Determining the Etiology and Severity of the Infection
The first and most critical step is identifying the source and extent of the infection. Odontogenic infections typically arise from:
▪️ Pulpal necrosis
▪️ Periapical pathology
▪️ Periodontal infections
▪️ Pericoronal infections
Severity assessment must include evaluation of pain, swelling, fever, trismus, dysphagia, airway compromise, and fascial space involvement. Severe or rapidly spreading infections require urgent intervention due to the risk of systemic involvement.
II. Evaluation of Medical History and Immune Status
A comprehensive medical history is essential to identify conditions that may alter disease progression or treatment response. Patients with diabetes mellitus, immunosuppression, malignancies, or chronic systemic diseases are at higher risk for complications.
Understanding the patient’s immune status allows clinicians to anticipate aggressive disease behavior and tailor treatment accordingly.
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The decision to manage the infection on an outpatient or inpatient basis depends on:
▪️ Severity and anatomical spread
▪️ Presence of systemic signs
▪️ Airway involvement
▪️ Patient’s general health status
Hospitalization is mandatory when there is airway compromise, systemic toxicity, dehydration, or involvement of deep cervical or fascial spaces.
IV. Surgical Management
Surgical intervention is the primary treatment modality for odontogenic infections. This includes:
▪️ Elimination of the infection source (tooth extraction or endodontic treatment)
▪️ Incision and drainage of abscesses
▪️ Adequate debridement of necrotic tissue
Antibiotics alone are insufficient without proper surgical management, especially in established abscesses.
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Supportive care plays a crucial role in recovery. Patients with severe infections often require:
▪️ Hydration therapy
▪️ Pain control
▪️ Nutritional support to maintain immune function
Adequate caloric intake and fluid balance are essential, particularly in patients with fever, dysphagia, or prolonged infection.
VI. Appropriate Selection and Prescription of Antibiotics
Antibiotic therapy should be adjunctive, not a substitute for surgical treatment. Selection must be based on:
▪️ Likely causative microorganisms
▪️ Local antimicrobial resistance patterns
▪️ Patient allergies and systemic condition
Empirical therapy often targets aerobic and anaerobic oral flora, with adjustments made based on clinical response. Rational antibiotic use is critical to prevent antimicrobial resistance.
VII. Periodic Patient Evaluation
Continuous monitoring is essential to assess treatment effectiveness. Follow-up should include evaluation of:
▪️ Reduction in swelling and pain
▪️ Improvement in systemic symptoms
▪️ Restoration of function
Failure to improve within 48–72 hours necessitates reassessment of diagnosis, surgical adequacy, and antimicrobial therapy.
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The principles proposed by Peterson et al. provide a structured and reproducible approach to managing odontogenic infections. Their strength lies in emphasizing early surgical intervention, patient-centered care, and judicious antibiotic use. In the context of rising antimicrobial resistance, adherence to these principles is more relevant than ever in contemporary dental practice.
✍️ Conclusion
The successful management of odontogenic infections depends on strict adherence to evidence-based principles, including accurate diagnosis, timely surgical intervention, appropriate antibiotic selection, and close patient monitoring. Applying the Peterson protocol systematically reduces complications and improves clinical outcomes.
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▪️ Always identify and eliminate the primary source of infection
▪️ Assess systemic and immune status before treatment planning
▪️ Do not rely solely on antibiotics without surgical intervention
▪️ Re-evaluate patients regularly to ensure clinical resolution
▪️ Refer or hospitalize promptly when airway or systemic involvement is suspected
📚 References
✔ Peterson, L. J., Ellis, E., Hupp, J. R., & Tucker, M. R. (2012). Contemporary Oral and Maxillofacial Surgery (6th ed.). St. Louis, MO: Mosby Elsevier.
✔ Flynn, T. R. (2011). Principles and surgical management of head and neck infections. Oral and Maxillofacial Surgery Clinics of North America, 23(3), 355–365.
✔ Hupp, J. R., Tucker, M. R., & Ellis, E. (2019). Contemporary Oral and Maxillofacial Surgery (7th ed.). Elsevier.
✔ Brook, I. (2017). Microbiology and management of odontogenic infections. Oral and Maxillofacial Surgery Clinics of North America, 29(4), 435–444.
✔ Velasco M., I., & Soto N., R. (2012). Principios para el tratamiento de infecciones odontogénicas con distintos niveles de complejidad. Revista Chilena de Cirugía, 64(6), 586–598.
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