Periodontal diseases, ranging from gingivitis to aggressive periodontitis, differ significantly in severity, progression, etiology, and treatment.
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1. Definitions and Main Characteristics
1.1 Gingivitis
The mildest and most common form of periodontal disease, characterized by gum inflammation and bleeding, generally caused by plaque accumulation without loss of periodontal support tissues. Gingivitis is fully reversible with proper oral hygiene, flossing, and regular professional cleanings.
1.2 Periodontitis
Progression from untreated gingivitis, involving irreversible destruction of the periodontal ligament and alveolar bone. It results in periodontal pocket formation, gum recession, tooth mobility, and eventual tooth loss if left untreated. Management often requires deep scaling and root planing, sometimes combined with systemic antibiotics or surgical intervention.
1.3 Aggressive Periodontitis
A less common but highly destructive form of periodontitis, progressing rapidly—often in patients under 30 years old—with no apparent systemic disease. Key features include:
° Rapid attachment loss (≥ 2 mm/year) and alveolar bone destruction.
° Absence of systemic conditions explaining progression.
° Strong family history suggesting genetic predisposition.
° Hyperactive immune response with elevated mediators such as PGE₂ and IL-1β.
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➤ Gingivitis & Chronic Periodontitis: Initiated by plaque and calculus accumulation; aggravated by smoking, diabetes, genetic factors, stress, or inadequate oral hygiene.
➤ Aggressive Periodontitis (AP):
° Involves a complex interplay of genetic predisposition and host hypersensitivity, including neutrophil and monocyte dysfunction and altered antibody responses (Benza-Bedoya, 2009).
° Smoking worsens disease progression by impairing gingival microcirculation, modulating immune response, and favoring pathogenic bacterial colonization.
° Highly virulent bacteria such as Aggregatibacter actinomycetemcomitans produce collagenases, leukotoxins, and other toxins that inhibit periodontal tissue repair.
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4. Diagnosis and Clinical Management
➤ Gingivitis: Clinical diagnosis; managed with improved oral hygiene, patient education, and professional cleanings.
➤ Periodontitis: Requires periodontal probing, radiographic assessment, and deep scaling and root planing; advanced cases may need surgical therapy or systemic antibiotics.
➤ Aggressive Periodontitis:
° Differential diagnosis involves detailed history, comprehensive periodontal examination, and ruling out systemic conditions.
° Treatment strategies include:
- Initial phase: Intensive plaque control, reinforcement of interdental cleaning.
- Corrective phase: Deep scaling, root planing, removal of defective restorations, and caries treatment.
- Regenerative or surgical phase: Periodontal surgery, regenerative procedures, and implant placement as needed.
- Maintenance: Highly individualized, with close monitoring due to rapid progression risk.
💬 Discussion
Gingivitis, chronic periodontitis, and aggressive periodontitis represent different points along the periodontal disease spectrum. Gingivitis is entirely reversible, while advanced forms require intensive interventions. Early detection is critical, particularly for aggressive periodontitis, which has distinct genetic, immunologic, and microbiologic profiles requiring specialized clinical management.
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° Gingivitis is an early, reversible, and highly manageable periodontal condition.
° Chronic periodontitis involves irreversible tissue destruction and requires professional periodontal therapy.
° Aggressive periodontitis progresses rapidly in otherwise healthy young individuals and demands prompt, specialized intervention and long-term follow-up.
📚 References
✔ Andrii Iemelyanenko. (2025, April 12). What Is the Difference Between Gingivitis and Periodontitis? Health.com. Retrieved from https://www.health.com/gingivitis-vs-periodontitis-11684200
✔ Nico De Pasquale. (2025, May 29). Healthy Gums vs. Unhealthy Gums: How To Tell the Difference. Health.com. Retrieved from https://www.health.com/healthy-vs-unhealthy-gums-11698782
✔ Benza-Bedoya, R. (2009). Periodontitis agresiva: Clasificación, características clínicas y etiopatogenia. Acta Odontológica Venezolana, 47(3). Retrieved from https://ve.scielo.org/scielo.php?pid=S0001-63652009000300020&script=sci_arttext
✔ Benza-Bedoya, R. (2009). Periodontitis agresiva: Diagnóstico y tratamiento. Acta Odontológica Venezolana, 47(4). Retrieved from https://homolog-ve.scielo.org/scielo.php?pid=S0001-63652009000400019&script=sci_arttext
✔ Medigraphic. (2018). Aggressive Periodontitis: Diagnosis and Clinical Management. Odovtos - International Journal of Dental Sciences, 20(3). Retrieved from https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=76787
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