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domingo, 30 de noviembre de 2025

Mouth Breathing in Children and Adults: Why It Is Harmful and How to Manage It

Tooth Extraction

Mouth breathing is a chronic dysfunctional breathing pattern linked to anatomical obstruction, habits, and sleep-related disorders.

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Its long-term consequences affect craniofacial development, oral health, systemic physiology, and quality of life. Early diagnosis and intervention are essential to prevent irreversible changes, particularly in children.

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Introduction
Mouth breathing refers to the predominant use of the oral cavity instead of the nose for airflow at rest. While occasional mouth breathing during a cold or intense exercise is normal, persistent oral respiration is clinically significant. Research shows that chronic mouth breathing disrupts nasal filtration, alters muscle activity, modifies dental arch development, and contributes to both malocclusions and sleep-disordered breathing (Zaghi et al., 2022). Early identification is crucial because craniofacial structures in children are still developing and more susceptible to functional changes.

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Causes of Mouth Breathing

➤ Anatomical Causes
▪️ Adenoid or tonsillar hypertrophy
▪️ Deviated nasal septum
▪️ Chronic allergic rhinitis
▪️ Nasal polyps
▪️ Inferior turbinate hypertrophy

➤ Functional and Behavioral Causes
▪️ Habitual open-mouth posture
▪️ Thumb sucking or prolonged pacifier use
▪️ Incorrect resting tongue position
▪️ Orofacial muscle hypotonia

➤ Sleep-Related Causes
▪️ Obstructive Sleep Apnea (OSA)
▪️ Primary snoring
▪️ Sleep-disordered breathing secondary to obesity

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Clinical Consequences in Children

➤ Craniofacial Growth Alterations
Chronic mouth breathing can redirect mandibular and maxillary growth patterns, producing the classic long-face syndrome (adenoid facies). Associated findings include:
▪️ Narrow maxilla
▪️ High palatal vault
▪️ Increased lower facial height
▪️ Posterior crossbite
▪️ Class II malocclusion tendencies

➤ Oral Health Impacts
▪️ Increased risk of dental caries due to reduced salivary flow
▪️ Gingival inflammation
▪️ Halitosis
▪️ Lip incompetence and dry mucosa

➤ Systemic and Behavioral Consequences
▪️ Daytime fatigue
▪️ Learning difficulties
▪️ Reduced concentration
▪️ Behavioral issues resembling ADHD
▪️ Poor sleep quality

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Clinical Consequences in Adults

➤ Oral and Periodontal Effects
Persistent oral breathing in adults often leads to:
▪️ Chronic xerostomia
▪️ Gingivitis and periodontitis progression
▪️ Higher susceptibility to root caries

➤ Respiratory and Sleep Effects
▪️ Snoring
▪️ Sleep-disordered breathing
▪️ Reduced oxygen saturation during sleep
▪️ Morning headaches

➤ Musculoskeletal and Postural Changes
▪️ Forward head posture
▪️ Neck and shoulder tension
▪️ Temporomandibular joint (TMJ) discomfort

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Diagnosis

➤ Clinical Evaluation
A comprehensive assessment includes:
▪️ Nasal patency examination
▪️ Lip competence observation
▪️ Tongue posture evaluation
▪️ Adenoid/tonsillar inspection
▪️ Cervicofacial posture assessment

➤ Complementary Exams
▪️ Lateral cephalometric radiograph
▪️ Nasal endoscopy (ENT evaluation)
▪️ Sleep study if OSA is suspected

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Evidence-Based Treatment

➤ Treatment in Children
Management depends on etiology and severity:
▪️ Adenotonsillectomy for obstructive hypertrophy
▪️ Allergy control (intranasal corticosteroids or antihistamines under medical guidance)
▪️ Maxillary expansion (RPE, SME) to widen nasal cavity and improve airflow
▪️ Myofunctional therapy to correct oral posture
▪️ Discontinuation of harmful habits

➤ Treatment in Adults
▪️ Nasal obstruction management (surgical or medical depending on case)
▪️ CPAP if associated with OSA
▪️ Orthodontic or orthognathic treatment when skeletal discrepancies persist
▪️ Orofacial myofunctional training

📊 Comparative Table: Nasal Breathing vs. Mouth Breathing

Aspect Advantages Limitations
Nasal Breathing Filters, warms and humidifies air; supports optimal craniofacial growth Limited during obstruction or anatomical deviations
Mouth Breathing Allows airflow when nasal passages are blocked Leads to malocclusions, dry mouth, poor sleep and systemic effects

💬 Discussion
Chronic mouth breathing is not a simple habit; it is a multifactorial condition with structural, functional, and behavioral consequences. Evidence shows that early intervention produces better outcomes, especially in the pediatric population where craniofacial growth can still be redirected. Adults, on the other hand, often require combined therapies rather than single-modality treatment. A multidisciplinary approach—pediatric dentistry, ENT, orthodontics, speech therapy, sleep medicine—is essential for long-term success.

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✍️ Conclusion
Mouth breathing substantially affects oral health, craniofacial development, systemic physiology, and sleep quality. Early diagnosis and targeted intervention are essential to prevent irreversible complications. Both adults and children benefit from an individualized management plan addressing nasal obstruction, soft-tissue dysfunction, and skeletal discrepancies.

🔎 Recommendations
▪️ Evaluate nasal patency and adenoid/tonsil size in all mouth-breathing children.
▪️ Implement orthodontic expansion when indicated.
▪️ Consider ENT referral early when obstruction is suspected.
▪️ Educate parents about the impact of oral habits on breathing.
▪️ Incorporate myofunctional therapy as part of long-term rehabilitation.
▪️ For adults, screen for sleep-disordered breathing before starting treatment.

📚 References

✔ Villa, M. P., Evangelisti, M., Barreto, M., Cecili, M., & Kaditis, A. G. (2017). Nasal obstruction in children: A clinical review. International Journal of Pediatric Otorhinolaryngology, 99, 81–88. https://doi.org/10.1016/j.ijporl.2017.05.029
✔ Zaghi, S., Patel, P., Barber, R., & Guilleminault, C. (2022). Sleep disordered breathing, mouth breathing, and craniofacial development: The role of myofunctional therapy. Sleep Medicine Reviews, 61, 101572. https://doi.org/10.1016/j.smrv.2021.101572
✔ Camacho, M., Certal, V., Abdullatif, J., et al. (2015). Myofunctional therapy to treat obstructive sleep apnea: A systematic review and meta-analysis. Sleep, 38(5), 669–675. https://doi.org/10.5665/sleep.4652

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sábado, 29 de noviembre de 2025

When Should an Infected Tooth Be Extracted? Updated Criteria for Primary and Permanent Dentition

Tooth Extraction

The decision to extract an infected tooth requires a careful assessment of the severity of the infection, the prognosis of the tooth, and the systemic risks for the patient.

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In both primary and permanent dentition, timely diagnosis prevents the progression of infection, reduces pain, and avoids complications such as cellulitis, osteomyelitis, or damage to successor teeth.

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Understanding Dental Infections in Children and Adults
Dental infections originate from bacterial invasion into the pulp chamber, leading to pulpitis, necrosis, and eventually periapical pathology. Treatment options vary depending on whether the tooth can be restored, the extent of bone destruction, and the patient’s age.

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Signs and Symptoms That Indicate a Tooth May Need Extraction

➤ Primary Teeth
▪️ Persistent dental abscess or fistula despite prior treatment
▪️ Severe root resorption affecting tooth stability
▪️ Pathological mobility not due to normal exfoliation
▪️ Presence of a cystic lesion associated with the primary tooth
▪️ Infection compromising the permanent successor, causing hypoplasia or displacement
▪️ Extensive crown destruction preventing pulpotomy or pulpectomy
▪️ Non-restorable tooth due to decay or trauma

➤ Permanent Teeth
▪️ Irreversible pulpitis with poor restorative prognosis
▪️ Vertical root fracture confirmed clinically or radiographically
▪️ Advanced periodontal disease with mobility grade III
▪️ Non-restorable decay extending subgingivally
▪️ Recurrent infection after endodontic treatment with no predictable retreatment success
▪️ Extensive bone loss around the tooth due to chronic infection
▪️ Systemic involvement: fever, swelling, or cellulitis spreading to fascial spaces

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Evidence-Based Treatment Options Before Considering Extraction

➤ Primary Dentition
▪️ Pulpotomy (for reversible pulp inflammation)
▪️ Pulpectomy (in select cases where canals are accessible and root structure remains)
▪️ Antibiotics only when systemic involvement is present; antibiotics do not replace definitive treatment

➤ Permanent Dentition
▪️ Root canal therapy
▪️ Periodontal therapy in cases of combined endo-perio lesions
▪️ Endodontic retreatment or apical surgery when feasible
If the prognosis remains unfavorable, extraction becomes the safest option.

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Indications for Immediate Extraction

▪️ Rapidly spreading infection, facial swelling, difficulty swallowing, or systemic signs
▪️ Non-restorable tooth structure
▪️ Extensive periapical destruction
▪️ Tooth acting as a reservoir of infection in medically compromised patients
▪️ Teeth interfering with the eruption path of permanent successors (primary teeth)

📊 Comparative Table: Extraction Criteria in Primary vs. Permanent Teeth

Aspect Advantages Limitations
Primary Teeth: Early Extraction of Infected Teeth Prevents damage to permanent successors; reduces recurrence Risk of space loss; may require a space maintainer
Permanent Teeth: Conservative Treatment First Preserves natural dentition; avoids prosthetic replacement Not viable if tooth is non-restorable or infection persists

💬 Discussion
Determining when to extract an infected tooth requires integrating clinical findings, radiographic evidence, child development considerations, and patient history. Primary teeth demand careful evaluation due to the close relationship with permanent buds. For permanent teeth, the decision prioritizes long-term oral health, potential restoration success, and systemic risk.

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✍️ Conclusion
An infected tooth requires extraction when restorative options are no longer viable, when infection threatens systemic health, or when the tooth compromises normal dental development. Evidence-based assessment ensures safe outcomes for both children and adults, reducing complications and supporting long-term oral health.

🔎 Recommendations
▪️ Evaluate both clinical and radiographic findings before extraction.
▪️ Prioritize conservative treatments when prognosis is acceptable.
▪️ In pediatric patients, assess potential harm to permanent successors.
▪️ In adults, consider systemic risk factors such as diabetes or immunosuppression.
▪️ Educate caregivers about early signs of infection to avoid severe complications.

📚 References

✔ American Academy of Pediatric Dentistry. (2022). Pulp therapy for primary and immature permanent teeth. AAPD Clinical Guidelines. https://www.aapd.org
✔ American Dental Association. (2020). Management of dental infections. ADA Evidence-Based Guidelines. https://www.ada.org
✔ Gomes, B. P. F. A., Fernandes, A. M., Jacinto, R. C., Zaia, A. A., Ferraz, C. C. R., & Souza-Filho, F. J. (2022). Microbial profile of infected primary teeth. International Journal of Paediatric Dentistry, 32(1), 32–40.
✔ Segura-Egea, J. J., Gould, K., Şen, B. H., et al. (2017). Antibiotics in endodontics: A review. International Endodontic Journal, 50(12), 1169–1184.
✔ Trope, M., & Chivian, N. (2020). The role of endodontics after dental trauma. Dental Clinics of North America, 64(1), 197–210.

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Protocols for the Management of Dentoalveolar Trauma in Children: Updated Clinical Guidelines

Dentoalveolar Trauma

Dentoalveolar trauma in children requires rapid diagnosis, structured decision-making, and age-appropriate treatment protocols.

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Introduction
Dentoalveolar trauma represents one of the most frequent pediatric dental emergencies, with an incidence peak in children aged 8 to 12 years. Injuries may affect the teeth, periodontal ligament, alveolar bone, and soft tissues. Proper management relies on accurate classification, immediate stabilization, and long-term monitoring to prevent complications such as pulp necrosis, ankylosis, or tooth loss.

1. Diagnosis and Initial Assessment
A systematic evaluation includes:

▪️ Trauma history: mechanism, timing, contamination.
▪️ Clinical examination: tooth mobility, displacement, soft-tissue injuries.
▪️ Radiographic assessment: periapical radiographs or occlusal views to detect fractures or displacement.
▪️ Assessment for non-accidental injury in very young children.

Key diagnostic criteria involve identifying the type of injury according to the International Association of Dental Traumatology (IADT) classification.

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2. Common Types of Dentoalveolar Trauma in Children

2.1. Concussion and Subluxation
➤ Features: Tenderness, mobility without displacement.
➤ Management: Occlusal relief if needed; soft diet for 7–10 days; periodic monitoring for pulp vitality.

2.2. Luxation Injuries
➤ Lateral luxation: Displacement with alveolar fracture; reposition and splint for 4 weeks.
➤ Extrusion: Gentle repositioning and flexible splinting for 2 weeks.
➤ Intrusion:
▪️ Primary teeth: allow spontaneous re-eruption.
▪️ Permanent teeth: spontaneous repositioning or orthodontic repositioning depending on root development.

2.3. Dental Avulsion
➤ Primary teeth: Replantation not recommended.
➤ Permanent teeth: Immediate replantation is the gold standard when feasible.
▪️ Transport medium: HBSS, milk, saline.
▪️ Splint: Flexible, 2 weeks.
▪️ Systemic antibiotics may be indicated (amoxicillin or doxycycline depending on age).

2.4. Crown and Root Fractures
➤ Uncomplicated fractures: Composite restoration.
➤ Complicated fractures: Pulp therapy based on stage of root development.
➤ Root fractures: Repositioning and 4-week splint.

2.5. Alveolar Process Fractures
➤ Repositioning of the segment and 4–6 week rigid splinting.

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3. Follow-Up Protocols
Follow-up intervals recommended by the IADT:

▪️ 1 week, 1 month, 3 months, 6 months, and 1 year, then annually for 5 years.
▪️ Pulp vitality monitoring: thermal, electric tests, and radiographs.
Early detection of pulp necrosis, pulp canal obliteration, or inflammatory root resorption is essential.

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4. Prevention Strategies

▪️ Use of mouthguards during sports.
▪️ Parental education on safe home environments.
▪️ Management of behavioral conditions (e.g., ADHD) associated with higher trauma incidence.

📊 Comparative Table: Splint Options in Pediatric Dental Trauma

Aspect Advantages Limitations
Flexible Splints Promote periodontal healing; recommended by IADT Not suitable for alveolar fractures requiring rigid fixation
Rigid Splints Provide stability for alveolar process fractures Higher risk of ankylosis and root resorption in teeth

💬 Discussion
Management of dentoalveolar trauma requires prompt intervention, but treatment decisions must consider the child’s age, tooth type, root development, and prognosis. Evidence indicates that improper or delayed management increases risks of pulp necrosis, ankylosis, and tooth loss. The IADT 2020 guidelines emphasize minimally invasive approaches, flexible splints, and reduced use of antibiotics.
Interdisciplinary collaboration between pediatric dentists, endodontists, and radiologists improves long-term outcomes.

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✍️ Conclusion
Effective management of pediatric dentoalveolar trauma relies on accurate diagnosis, timely stabilization, and evidence-based treatment protocols. Long-term follow-up is essential to prevent complications such as root resorption or pulp necrosis. Prevention strategies significantly reduce incidence and severity. Updated IADT guidelines remain the gold standard in clinical practice.

🔎 Recommendations
▪️ Use IADT-based classification for all trauma cases.
▪️ Prioritize minimally invasive repositioning techniques and flexible splints.
▪️ Avoid unnecessary replantation of primary teeth.
▪️ Provide written post-operative instructions to parents.
▪️ Schedule structured follow-ups for at least 12 months after injury.

📚 References

✔ American Academy of Pediatric Dentistry. (2024). Guideline on Management of Acute Dental Trauma. AAPD Reference Manual.
✔ Andersson, L., Andreasen, J. O., Day, P., Heithersay, G., Trope, M., DiAngelis, A., Kenny, D. J., Sigurdsson, A., Bourguignon, C., & Flores, M. T. (2020). International Association of Dental Traumatology guidelines for the management of traumatic dental injuries. Dental Traumatology, 36(4), 314–330. https://doi.org/10.1111/edt.12589
✔ Malikaew, P., Watt, R. G., & Sheiham, A. (2003). Dental injuries in primary teeth. Dental Traumatology, 19(5), 252–256. https://doi.org/10.1034/j.1600-9657.2003.00204.x
✔ Flores, M. T. (2002). Traumatic injuries in the primary dentition. Dental Traumatology, 18(6), 287–298. https://doi.org/10.1034/j.1600-9657.2002.00122.x

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jueves, 27 de noviembre de 2025

Forceps Selection and Techniques by Tooth Type: Updated Clinical Guidelines

Oral Surgery

Forceps selection directly influences the efficiency, safety, and predictability of dental extractions. Evidence shows that matching the correct instrument to the tooth anatomy, root morphology, and bone density significantly reduces complications such as root fracture, alveolar bone damage, and postoperative pain.

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Introduction
Tooth extraction remains a core procedure in clinical dentistry. The choice of forceps must consider crown morphology, root curvature, bone density, and the periodontal condition of each tooth. A correct forceps selection enhances mechanical advantage, minimizes alveolar trauma, and improves overall procedure efficiency and patient outcomes.

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Forceps Selection by Tooth Type

1. Maxillary Teeth (Upper Teeth)

➤ Maxillary Incisors
▪️ Recommended forceps: No. 1 or No. 99C
▪️ Key features: Straight beaks adapted to conical roots.
▪️ Technique notes: Labial-lingual rocking with minimal rotation.

➤ Maxillary Canines
▪️ Recommended forceps: No. 150
▪️ Key features: Stronger root requiring controlled luxation.
▪️ Technique notes: Avoid excessive rotation because of long root length.

➤ Maxillary Premolars
▪️ Recommended forceps: No. 150A
▪️ Key features: Thin beaks fit narrow neck morphology.
▪️ Technique notes: Buccal forces are preferred due to thin cortical bone.

➤ Maxillary Molars
▪️ Recommended forceps: No. 53R/53L or No. 210S (third molars)
▪️ Key features: Curved beaks designed to engage diverging roots.
▪️ Technique notes: Buccal traction with controlled figure-eight motion.

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2. Mandibular Teeth (Lower Teeth)

➤ Mandibular Incisors
▪️ Recommended forceps: No. 151
▪️ Key features: Narrow beaks for compressed cervical area.
▪️ Technique notes: Labial traction, minimal rotation.

➤ Mandibular Canines
▪️ Recommended forceps: No. 151 or No. 13
▪️ Key features: Strong root anchorage.
▪️ Technique notes: Luxation must be slow to avoid root fracture.

➤ Mandibular Premolars
▪️ Recommended forceps: No. 151A
▪️ Key features: Versatile angulation for narrow necks.
▪️ Technique notes: Gentle rotation is possible due to single-root anatomy.

➤ Mandibular Molars
▪️ Recommended forceps: No. 17 or No. 23 ("cowhorn")
▪️ Key features: Deep beaks fit furcations in multirooted molars.
▪️ Technique notes: For No. 23, use pumping motion to elevate tooth coronally.

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Principles of Atraumatic Extraction

▪️ Adequate luxation before applying traction.
▪️ Stabilizing the alveolus with counter-pressure.
▪️ Avoiding excessive rotational forces in multi-rooted teeth.
▪️ Ensuring correct fulcrum position to avoid cortical plate fracture.

📊 Comparative Table: Differences Between Adult and Pediatric Forceps

Aspect Advantages Limitations
Size & Dimensions Pediatric forceps are smaller and designed to fit limited oral openings; reduce soft-tissue interference. Smaller size provides less mechanical advantage and may limit grip on large or multi-rooted teeth.
Beak Design & Adaptation Pediatric beaks are shaped to match primary tooth crowns and slender roots, minimizing accidental damage to developing permanent teeth. Adult beaks offer broader purchase on permanent tooth anatomy; pediatric beaks may not engage adequately on malformed or erupted permanent teeth.
Handle Length & Leverage Shorter handles improve control in small mouths and reduce operator hand fatigue during pediatric procedures. Reduced leverage can make difficult extractions more challenging and may necessitate adjunctive techniques (e.g., elevators).
Trauma Risk & Clinical Use Pediatric forceps tend to be less traumatic to alveolar bone and adjacent tissues when used correctly; suited for atraumatic extractions in children. Adult forceps provide greater force and may cause collateral damage in small jaws; pediatric instruments may be unavailable in some settings.
💬 Discussion
Current literature emphasizes that extraction success depends not only on clinician skill but also on matching forceps geometry to tooth anatomy. Forceps with anatomical beaks distribute forces more efficiently, reducing risk of alveolar bone damage. However, universal forceps remain valuable in pediatric and general practice settings due to their adaptability.
Newer ergonomic designs and improved steel alloys have increased precision and tactile feedback, but biomechanical principles remain unchanged: controlled force, correct fulcrum, and proper luxation are essential.

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✍️ Conclusion
Correct forceps selection according to tooth type enhances procedural predictability, minimizes trauma, and improves postoperative healing. Universal forceps are practical, but anatomy-specific instruments provide superior biomechanical efficiency in complex extractions. Mastery of both instrument selection and atraumatic technique remains essential for safe and successful practice.

🔎 Recommendations
▪️ Use universal forceps for routine anterior extractions but switch to anatomy-specific instruments for molars.
▪️ Apply controlled luxation before traction to minimize fractures.
▪️ Incorporate clinical radiographic evaluation to anticipate root divergence, curvature, or anomalies.
▪️ Consider specialized forceps (#23 cowhorn) for mandibular molars with advanced interradicular bone loss.

📚 References

✔ Bouloux, G. F., Steed, M. B., & Perciaccante, V. J. (2007). Complications of third molar surgery. Oral and Maxillofacial Surgery Clinics of North America, 19(1), 117–128. https://doi.org/10.1016/j.coms.2006.11.009
✔ Hupp, J. R., Ellis, E., & Tucker, M. R. (2018). Contemporary Oral and Maxillofacial Surgery (7th ed.). Elsevier.
✔ Peterson, L. J., Ellis, E., Hupp, J. R., & Tucker, M. R. (2012). Peterson’s Principles of Oral and Maxillofacial Surgery (3rd ed.). PMPH-USA.
✔ Tsichlaki, A., & Jones, K. (2019). Mechanical considerations in dental extractions. British Dental Journal, 226, 403–410. https://doi.org/10.1038/s41415-019-0077-8

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How Much Fluoride Is Too Much? Updated Guidelines for Children (Including 2025 FDA Recommendations)

Fluoride

The use of fluoride in pediatric dentistry remains a cornerstone for preventing dental caries. However, updated safety concerns and new regulatory actions by the U.S. Food and Drug Administration (FDA, 2025) have shifted recommendations regarding systemic fluoride supplementation.

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Overview of Fluoride and Its Clinical Relevance
Fluoride enhances enamel resistance, promotes remineralization, and reduces cariogenic bacterial activity. Despite these benefits, excessive systemic fluoride exposure during tooth development can lead to varying degrees of fluorosis. Determining the appropriate dosage depends on age, exposure sources, and caries risk.

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Updated FDA Position (2025): Key Points
The FDA’s 2025 update drastically changes how systemic fluoride supplements should be prescribed in children.

➤ Key regulatory updates include:
▪️ Restriction of oral fluoride supplements (drops/tablets) to children ≥3 years old, and only when they are at high caries risk.
▪️ Identification that many systemic fluoride products were never FDA-approved, prompting regulatory action to remove them from circulation.
▪️ Emphasis on topical fluoride products as the primary preventive strategy, which remain unaffected and are considered safe.
▪️ Recognition that routine systemic supplementation provides limited benefit in primary dentition, raising concerns about unnecessary exposure.
▪️ Consideration of potential systemic effects (e.g., gut microbiome alterations), though evidence remains inconclusive.

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Important note:
These updated recommendations override traditional supplementation tables commonly used in pediatric dentistry. Any systemic fluoride dosing must now be limited to older children (≥3 years), justified by documented high caries risk, and based on approved products available in the clinician’s region.

Evidence-Based Fluoride Recommendations for Children

1. Topical Fluoride (Safe and Preferred)

➤ Fluoride toothpaste (1000–1500 ppm):
▪️ Smear for less than 03 years; pea-sized for ≥3 years.
➤ Fluoride varnish (5% NaF):
▪️ Twice yearly for low risk; 3–4 times yearly for high risk.
➤ Rinses (0.05% NaF daily):
▪️ For children ≥6 years with moderate/high caries risk.

2. Systemic Fluoride (Now Highly Restricted)
Following the FDA 2025 guidance, systemic supplements should:

▪️ Be considered only for children ≥3 years.
▪️ Be prescribed only in high-risk cases.
▪️ Avoid use in areas with optimally fluoridated water.
▪️ Use the minimal effective dose if supplementation is deemed necessary.

Classic dosing tables remain referenced in literature but may not align with FDA restrictions.

📊 Comparative Table: Topical vs. Systemic Fluoride in Children (2025 Update)

Aspect Advantages Limitations
Topical Fluoride High caries prevention; minimal systemic absorption; FDA-safe Requires parental supervision to avoid ingestion
Systemic Fluoride (2025 restricted) Useful only in high-risk children without fluoridated water FDA restrictions; risk of fluorosis; limited benefit in primary dentition

💬 Discussion
The evolution of fluoride guidelines reflects a broader shift toward individualized, risk-based caries prevention. The 2025 FDA regulatory action emphasizes the importance of safety, approval status, and actual clinical benefit, particularly regarding systemic fluoride products. Meanwhile, topical fluoride modalities remain the most effective and safest strategies for preventing caries without increasing fluorosis risk.

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🔎 Recommendations
▪️ Prioritize topical fluoride as the primary preventive approach.
▪️ Use systemic fluoride only when strictly indicated, following updated FDA criteria.
▪️ Evaluate each child’s total fluoride exposure, including water, toothpaste ingestion, and diet.
▪️ Educate parents on safe brushing practices to minimize swallowing.
▪️ Monitor for early signs of dental fluorosis in high-risk communities.

✍️ Conclusion
Determining how much fluoride is “too much” requires balancing preventive benefits with safety, especially in developing dentition. The 2025 FDA restrictions reinforce a conservative approach to systemic fluoride use and highlight topical fluoride as the mainstay of pediatric caries prevention. Clinicians must remain updated and tailor fluoride exposure to each child’s unique risk factors.

📚 References

✔ American Dental Association. (2023). Fluoride: Topical and Systemic Benefits. https://www.ada.org
✔ Centers for Disease Control and Prevention. (2024). Community water fluoridation: Recommendations and guidelines. https://www.cdc.gov/fluoridation/
✔ Contemporary Pediatrics. (2025). FDA restricts sale of unapproved ingestible fluoride drugs for children. https://www.contemporarypediatrics.com/view/fda-restricts-sale-of-unapproved-ingestible-fluoride-drugs-for-children
✔ U.S. Food and Drug Administration. (2025a). Ingestible Fluoride Drug Products: Public Health Advisory. https://www.fda.gov/news-events/public-health-focus/ingestible-fluoride-drug-products
✔ U.S. Food and Drug Administration. (2025b). FDA acts to remove unapproved systemic fluoride drug products for children. https://www.fda.gov/news-events/press-announcements/

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