Ver todoCapacitación

Medicina Bucal

Endodoncia

ÚLTIMAS NOTICIAS

sábado, 22 de noviembre de 2025

Pulpotomy vs. Pulpectomy in Primary Teeth: A Contemporary Clinical Guide

Pulpotomy - Pulpectomy

Vital pulp therapy in primary teeth is a cornerstone of pediatric dental treatment. Among the most common procedures are pulpotomy, which conserves some of the radicular pulp, and pulpectomy, which removes all pulp tissue.

📌 Recommended Article :
Dental Article 🔽 Manual of diagnosis and pulp treatment in non-vital primary teeth ... Non-vital teeth are those whose nerves lack vitality and there is no blood flow inside. This may be due to deep caries or dental trauma that irreversibly affects the dental pulp.
Understanding the clinical indications, long-term outcomes, advantages, and limitations of each technique is essential for optimizing patient care and maintaining primary teeth until exfoliation.

Advertisement

Background and Rationale
Primary teeth differ significantly from permanent teeth in morphology and physiology, notably in their root anatomy, resorption patterns, and innervation. Current pediatric dentistry guidelines (e.g., AAPD) describe pulpotomy as indicated when coronal pulp is inflamed but radicular pulp remains vital. Meanwhile, pulpectomy is generally reserved for cases with necrosis, irreversible pulpitis, or radiographic pathology.

📌 Recommended Article :
Video 🔽 Pulpectomy. Step-by-Step Procedure - Access, Preparation, and Obturation ... We share the step-by-step procedure of a pulpectomy performed with rotary files. In this video we can observe the opening, chemomechanical preparation and obturation.
Clinical Evidence: Success Rates & Comparative Outcomes

➤ Randomized & Controlled Trials
▪️ A multicenter RCT comparing cervical pulpotomy (with calcium-enriched mixture cement) versus pulpectomy (Metapex) in primary molars with irreversible pulpitis found no significant difference in clinical and radiographic success rates. PubMed
▪️ In a split-mouth randomized trial on primary incisors with vital pulp exposure, pulpotomy (formocresol) and pulpectomy (zinc-oxide-eugenol) showed similar 12-month success, with survival rates of ~82% vs ~74%, respectively (not statistically significant).

➤ Observational and Cohort Studies
A retrospective cohort study of 876 primary molars reported that iRoot BP Plus pulpotomy had a significantly better long-term prognosis (survival over 48 months) than Vitapex pulpectomy.
A survival analysis of pulpectomy under general anesthesia found that failures usually stemmed from incomplete tissue removal and complexity of root canal systems in primary molars.

➤ Systematic Reviews & Meta-Analyses
▪️ A large Cochrane-type review concluded that MTA (mineral trioxide aggregate) is superior to formocresol and calcium hydroxide for pulpotomy in primary teeth.
▪️ Another systematic review and meta-analysis demonstrated high clinical and radiographic success for pulpotomy in primary teeth with irreversible pulpitis, suggesting that inflammation might be confined to the coronal pulp in many cases.

📊 Comparative Table: Pulpotomy vs Pulpectomy in Primary Teeth

Aspect Advantages Limitations
Tissue preservation Maintains some vital radicular pulp, encouraging natural resorption May leave inflamed tissue if diagnosis is incorrect
Procedure time & behavior Generally faster and less technically demanding; better tolerated in uncooperative children Hemostasis must be achieved; persistent bleeding may complicate treatment
Long-term survival High survival rates over several years (e.g., > 70% at 48 months with bioceramic pulpotomy) :contentReference[oaicite:9]{index=9} Success depends on correct diagnosis and use of proven medicaments (e.g., MTA) :contentReference[oaicite:10]{index=10}
Indications Irreversible pulpitis with vital radicular tissue; minimal radiographic pathology Not suitable if necrosis, internal/external resorption, or periapical infection present :contentReference[oaicite:11]{index=11}
Risks & complications Lower risk of overfilling; less risk to developing permanent tooth bud Risk of failure if improper agent or poor seal; possible internal resorption
Restoration after treatment Can be restored with stainless steel crowns or other durable restorations with good retention :contentReference[oaicite:12]{index=12} Coronal leakage or microleakage can compromise outcome if restoration fails

💬 Discussion
The body of evidence suggests that pulpotomy and pulpectomy both have clinically acceptable success in primary teeth when properly indicated. Notably:

▪️ Pulpotomy, especially when using modern materials like MTA or bioceramic cements (e.g., iRoot BP Plus), demonstrates excellent long-term survival.
▪️ Pulpectomy, while more invasive, remains critical in cases of necrosis or when radiographic signs of pathology are present. However, it is technically demanding, particularly due to the complex canal anatomy of primary molars.
▪️ Systematic reviews consistently favor MTA over traditional agents like formocresol or calcium hydroxide for pulpotomy, due to better clinical and radiographic outcomes.
▪️ Patient-centered outcomes also favor more conservative therapy: pulpectomy has been associated with improved quality of life and lower dental anxiety compared to extraction, making it preferable over tooth loss.

Additionally, a recently registered RCT protocol aims to provide more rigorous evidence by comparing pulpotomy vs pulpectomy in primary molars with irreversible pulpitis over two years. This trial could potentially shift paradigms if pulpotomy proves non-inferior, given its lower invasiveness and patient burden.

📌 Recommended Article :
Dental Article 🔽 Mineral Trioxide Aggregate (MTA) in Pediatric Dentistry: Uses, Benefits, and Clinical Evidence ... Among them, Mineral Trioxide Aggregate (MTA) has emerged as a gold standard for pulp therapy, especially for its regenerative properties and sealing capability.
Recommendations for Clinical Practice

1. Case Selection Is Key
▪️ Use pulpotomy when the pulp is vital, bleeding is controlled, and no periapical pathology is evident.
▪️ Reserve pulpectomy for cases with necrosis, internal/external resorption, or evidence of interradicular/periapical disease.

2. Material Choice
▪️ Prefer MTA or bioceramic materials (e.g., iRoot BP Plus) for pulpotomy due to demonstrated higher success rates.
▪️ For pulpectomy, use resorbable filling materials compatible with primary tooth anatomy (e.g., Metapex, Vitapex), though evidence does not strongly favor one over another.

3. Behavior Management & Procedural Efficiency
▪️ Because pulpotomy is generally faster and less technique-sensitive, it may be better suited for younger or less cooperative children.
▪️ Ensure accurate diagnosis (clinical + radiographic) to minimize risk of failed treatment.

4. Follow-up Protocol
▪️ Schedule periodic clinical and radiographic reviews (e.g., 6 months, 12 months, annually) to monitor for signs of failure or resorption.
▪️ Optimize restorative sealing (e.g., stainless-steel crown) to reduce risk of microleakage.

5. Research and Continuous Learning
▪️ Stay updated with ongoing trials (e.g., the non-inferiority RCT of pulpotomy vs pulpectomy in primary molars) for evidence that may refine treatment guidelines.
▪️ Contribute to or audit long-term outcomes in your own practice to inform future decisions.

📌 Recommended Article :
Dental Article 🔽 Partial Pulpotomy in Pediatric Dentistry: Technique, Benefits, and Key Differences ... Partial pulpotomy offers a biologically favorable approach in cases of limited pulp inflammation, especially in traumatic pulp exposures or shallow carious lesions, promoting healing and long-term tooth survival.
✍️ Conclusion
In modern pediatric dentistry, both pulpotomy and pulpectomy remain viable options for managing pulpally involved primary teeth. While pulpotomy offers a more conservative and less time-consuming approach with excellent long-term survival—especially when using materials like MTA or bioceramics—pulpectomy remains irreplaceable in cases of necrosis or advanced pathology. Clinicians should base their choice on careful diagnosis, patient behavior, material selection, and a commitment to follow-up. Together, these strategies help preserve primary teeth, maintain arch integrity, and support the well-being of pediatric patients.

📚 References

✔ Holan, G., & Fuks, A. B. (2015). The role of pulpectomy in the primary dentition. Pediatric Dentistry, 37(6), 559–566.
✔ Philip, N., Cherian, J. M., Mathew, M. G., et al. (2024). Treatment outcomes of pulpotomy versus pulpectomy in vital primary molars diagnosed with symptomatic irreversible pulpitis: protocol for a non-inferiority randomized controlled trial. BMC Oral Health, 24, 626. https://doi.org/10.1186/s12903-024-04411-6
✔ Li, J., Fan, W., Zhou, Y., Wu, L., Liu, W., & Huang, S. (2024). Pulpotomy versus pulpectomy in carious vital pulp exposure in primary incisors: a randomized controlled trial. BMC Dentistry.
✔ Xu, X., Chen, X., Wang, X., & Chen, J. (2023). Survival analysis of pulpotomy versus pulpectomy in primary molars with carious pulp exposure. International Endodontic Journal.
✔ Walsh, T., Clarke, M., Tsang, A., Marshman, Z., & Petrou, K. (2016). Pulp treatment for extensive decay in primary teeth. Cochrane Database of Systematic Reviews, (4), CD003220.
✔ American Academy of Pediatric Dentistry. (n.d.). Pulp Therapy for Primary and Immature Permanent Teeth. AAPD Policy.

📌 More Recommended Items

Management of Pulpal Infections in Primary Teeth: Evidence-Based Protocols 2025
Calcium Hydroxide in Pediatric Dentistry: Benefits and Limitations
Partial pulpotomy vs. Conventional (full) pulpotomy in primary teeth — a comparative, evidence-based review

Why Patients With Diabetes Develop Gingival Inflammation, Tooth Mobility, and Tooth Loss

Diabetes

This article examines why patients with diabetes commonly develop gingival inflammation, tooth mobility, and progressive tooth loss, emphasizing the interplay between hyperglycemia, immune dysfunction, periodontal pathogens, and tissue destruction.

📌 Recommended Article :
Dental Article 🔽 Why Does Diabetes Cause Dry Mouth? Understanding the Link Between Xerostomia and Blood Sugar Levels ... Since saliva plays a critical role in maintaining oral and systemic health, understanding the mechanisms behind xerostomia in diabetes is essential for prevention and management of related complications.
Introduction
Diabetes mellitus is recognized as one of the strongest systemic risk factors for periodontal disease. High blood glucose levels impair immune responses, alter the oral microbiome, and accelerate periodontal tissue breakdown. Understanding these mechanisms is essential for improving prevention and management strategies in diabetic populations.

Advertisement

Pathophysiology of Gingival Inflammation in Diabetes
Diabetes promotes chronic inflammation through several mechanisms:

▪️ Advanced glycation end products (AGEs) accumulate in tissues, triggering exaggerated inflammatory responses.
▪️ Neutrophil dysfunction reduces the host’s ability to control oral pathogens.
▪️ Microvascular impairment decreases oxygenation and nutrient delivery to periodontal tissues.

As a result, patients frequently exhibit red, swollen, and bleeding gums even with moderate plaque levels.

📌 Recommended Article :
Dental Article 🔽 Key Differences Between Gingivitis, Periodontitis, and Aggressive Periodontitis: Updated Clinical Review ... This academic article critically examines these distinctions based on current scientific evidence and emphasizes their clinical implications for dental professionals.
Reasons for Tooth Mobility in Diabetic Patients
Tooth mobility arises because:

▪️ Chronic hyperglycemia accelerates alveolar bone resorption.
▪️ Altered collagen metabolism weakens periodontal ligament fibers.
▪️ Persistent inflammation destroys connective tissue attachment.

These factors collectively lead to progressive periodontal breakdown, manifesting as increased probing depths, attachment loss, and mobility.

📌 Recommended Article :
Dental Article 🔽 Oral Manifestations of Systemic Diseases: Updated Clinical Review ... Due to its high vascularity and immune role, the oral cavity frequently reflects systemic conditions. In modern dentistry, recognizing these signs is key to preventive care and interdisciplinary treatment.
Mechanisms Leading to Tooth Loss
If untreated, the combination of inflammation, bone loss, and connective tissue destruction ultimately results in tooth loss. Key contributors include:

▪️ Excessive inflammatory mediators such as IL-1β and TNF-α.
▪️ Reduced wound healing capacity due to microvascular complications.
▪️ Increased susceptibility to destructive periodontal pathogens like Porphyromonas gingivalis.

Studies consistently show that poorly controlled diabetes is associated with a significantly higher risk of edentulism.

📌 Recommended Article :
Video 🔽 Can a tooth be extracted in diabetic patients? ... The dentist must take all precautions when caring for a diabetic patient, especially when performing a tooth extraction. A complete interrogation on the health of the patient and a correct clinical evaluation must be carried out beforehand.
Additional Factors that Worsen Periodontal Outcomes in Diabetes

▪️ Smoking
▪️ Poor glycemic control (HbA1c > 7%)
▪️ Hyposalivation
▪️ Altered oral microbiota
▪️ Delayed tissue repair

These factors explain why even well-motivated diabetic patients may experience rapid periodontal deterioration if systemic control is insufficient.

📊 Comparative Table: Clinical Indicators of Periodontal Damage in Diabetic Patients

Aspect Advantages Limitations
Periodontal Probing Depth Identifies early and advanced tissue breakdown Technique-sensitive; inflammation may alter readings
Radiographic Bone Loss Assessment Provides objective visualization of alveolar bone changes Cannot detect soft-tissue inflammation or early lesions
Tooth Mobility Evaluation Simple clinical indicator of disease progression Influenced by trauma, occlusion, or temporary inflammation
Bleeding on Probing (BOP) Useful marker for inflammatory activity Not always present in severe chronic cases in diabetics

💬 Discussion
There is strong bidirectional evidence linking diabetes and periodontal disease. Periodontitis worsens glycemic control, while uncontrolled diabetes accelerates periodontal destruction. This relationship underscores the importance of integrated dental and medical management. Regular periodontal therapy significantly improves both oral health outcomes and metabolic parameters.

📌 Recommended Article :
Dental Article 🔽 Prosecco Teeth: The Growing Dental Concern at Celebrations ... However, dental professionals are raising alarms about a condition termed "Prosecco teeth," highlighting the potential oral health risks associated with this sparkling beverage.
✍️ Conclusion
Patients with diabetes are more prone to gingival inflammation, tooth mobility, and tooth loss due to immune dysregulation, microvascular damage, elevated inflammatory mediators, and impaired wound healing. Early diagnosis, consistent periodontal therapy, and strict glycemic control are essential to prevent irreversible damage.

🔎 Recommendations
▪️ Conduct periodontal evaluations every 3–4 months for diabetic patients.
▪️ Emphasize glycemic control as part of periodontal therapy.
▪️ Encourage meticulous plaque control with interdental hygiene.
▪️ Provide tailored education on the oral-systemic health connection.
▪️ Collaborate closely with physicians to monitor metabolic status.

📚 References

✔ American Diabetes Association. (2023). Standards of medical care in diabetes–2023. Diabetes Care, 46(Supplement_1), S1–S291. https://doi.org/10.2337/dc23-SINT
✔ Mealey, B. L., & Ocampo, G. L. (2017). Diabetes mellitus and periodontal disease. Periodontology 2000, 44(1), 127–153. https://doi.org/10.1111/j.1600-0757.2006.00193.x
✔ Preshaw, P. M., Alba, A. L., Herrera, D., Jepsen, S., Konstantinidis, A., Makrilakis, K., & Taylor, R. (2012). Periodontitis and diabetes: A two-way relationship. Diabetologia, 55, 21–31. https://doi.org/10.1007/s00125-011-2342-y
✔ Taylor, G. W., & Borgnakke, W. S. (2008). Periodontal disease: Associations with diabetes, glycemic control and complications. Oral Diseases, 14(3), 191–203. https://doi.org/10.1111/j.1601-0825.2008.01442.x

📌 More Recommended Items

How to Treat Tonsil Stones
Top Antibiotics and Mouthwashes for Periodontal Treatment: Updated Guide with Doses and Benefits
Is Gingivitis or Periodontitis Contagious? A Scientific Overview of Transmission, Symptoms, and Microbiota

jueves, 20 de noviembre de 2025

Bioactive Materials in Pulpotomies: MTA, Biodentine and Emerging Alternatives

Bioactive Materials - Pulpotomies

Bioactive materials have transformed vital pulp therapy in pediatric dentistry. Mineral Trioxide Aggregate (MTA) and Biodentine remain the most reliable options due to their biocompatibility, sealing ability, and predictable dentin bridge formation.

📌 Recommended Article :
Dental Article 🔽 Management of Pulpal Infections in Primary Teeth: Evidence-Based Protocols 2025 ... This 2025 update provides a concise, evidence-based overview of pulpal infection management in primary teeth, following the latest AAPD 2024 classification and clinical protocols.
Newer agents such as bioceramic putties continue to expand treatment possibilities. Understanding the clinical performance and limitations of each material is essential for evidence-based decision-making in pulpotomies.

Advertisement

Introduction
Pulpotomy remains a widely used treatment for reversible pulp inflammation in primary teeth, aiming to maintain tooth vitality until exfoliation. Over the last two decades, bioactive materials have replaced traditional agents due to superior biological responses and reduced cytotoxicity. Current evidence strongly supports the use of MTA, Biodentine, and next-generation hydraulic calcium silicate cements as the materials of choice.
This article reviews the mechanisms, clinical performance, and limitations of the most relevant bioactive materials used in pediatric pulpotomies.

📌 Recommended Article :
Dental Article 🔽 Mineral Trioxide Aggregate (MTA) in Pediatric Dentistry: Uses, Benefits, and Clinical Evidence ... Preserving primary teeth until their natural exfoliation is a key goal in pediatric dentistry. Advances in bioactive materials have made this more predictable.
MTA: Mechanism and Clinical Behavior
Mineral Trioxide Aggregate (MTA) is one of the most documented pulpotomy materials. Key properties include its strong biocompatibility, high sealing ability, and promotion of dentin bridge formation.

➤ Advantages:
▪️ Releases calcium hydroxide, stimulating hard tissue formation.
▪️ Excellent marginal seal, preventing microleakage.
▪️ Proven long-term success rates in primary teeth.

➤ Limitations:
▪️ Difficult handling.
▪️ Long setting time.
▪️ Potential dentin and enamel discoloration due to bismuth oxide.
Large-scale systematic reviews continue to position MTA as a gold standard in partial and full pulpotomies.

📌 Recommended Article :
Dental Article 🔽 Pulpotec® in Pulpotomy: Composition, Indications, Protocol & Clinical Pros and Cons ... Pulpotec® is a radiopaque, non‑resorbable medicament widely used for pulpotomy/pulpitis treatment in vital primary and immature permanent molars, as well as for emergency root canal dressings.
Biodentine: A Calcium Silicate with Enhanced Handling
Biodentine is a high-purity tricalcium silicate cement developed to overcome practical limitations of MTA. Its faster setting time, improved mechanical properties, and higher biocompatibility make it ideal for pediatric use.

➤ Advantages:
▪️ Sets within 12 minutes.
▪️ Superior mechanical strength.
▪️ Does not stain tooth structure.
▪️ Promotes predictable tertiary dentin deposition.

➤ Limitations:
▪️ Cost may be higher in some regions.
▪️ Requires strict moisture control during placement.
Clinical trials show success rates comparable—sometimes superior—to MTA for primary teeth pulpotomies.

📌 Recommended Article :
Dental Article 🔽 Medications Used in Pulpotomies: Properties, Drawbacks, and Brand Names ... Pulpotomy is a conservative dental procedure aimed at preserving the vitality of the radicular pulp after removing the affected coronal pulp. This treatment is common in primary teeth and young permanent teeth.
New Bioceramic Alternatives
Recently introduced premixed bioceramic putties (e.g., EndoSequence Root Repair Material, TotalFill) offer excellent handling and consistent composition.

➤ Advantages:
▪️ Ready-to-use format.
▪️ No discoloration.
▪️ High radiopacity.

➤ Limitations:
▪️ Less long-term evidence compared to MTA and Biodentine.
▪️ Higher price point.
Emerging literature supports their use in vital pulp therapy, but they should currently be considered adjunctive rather than primary options.

📊 Comparative Table: Bioactive Materials Used in Pulpotomy

Aspect Advantages Limitations
MTA Excellent sealing ability; high biocompatibility; strong evidence base Long setting time; potential discoloration; difficult handling
Biodentine Fast setting time; no discoloration; improved mechanical properties Higher cost; requires moisture control
Bioceramic Putties Ready-to-use; radiopaque; stable composition Limited long-term data; higher cost

💬 Discussion
Bioactive materials demonstrate superior biological performance compared with traditional agents such as formocresol or ferric sulfate. Among all available options, MTA and Biodentine show the strongest evidence, high success rates, and favorable clinical outcomes.
Biodentine excels in handling and aesthetics, while MTA maintains unmatched historical and clinical validation. Next-generation bioceramics may eventually match these standards, but they still lack extensive longitudinal data in pediatric pulpotomies.

📌 Recommended Article :
Dental Article 🔽 Bioactive Biomaterials in Pulp Therapy and Necrosis Management in Pediatric Dentistry ... The evolution of pulp therapy in pediatric dentistry has shifted from traditional medicaments to bioactive biomaterials that promote regeneration and tissue healing.
✍️ Conclusion
Bioactive materials have significantly improved the prognosis of pulpotomies in primary teeth. MTA and Biodentine remain the most reliable choices, offering excellent sealing ability and biocompatibility. Although new bioceramic materials show promise, further research is needed to confirm long-term performance. Selecting the appropriate material should be based on clinical indication, handling needs, and evidence-based guidelines.

🔎 Recommendations
▪️ Prefer MTA or Biodentine for routine pediatric pulpotomies.
▪️ Use bioceramic putties in cases requiring enhanced handling or when discoloration is a concern.
▪️ Maintain strict isolation and moisture control to optimize clinical outcomes.
▪️ Follow radiographic and clinical follow-ups at 6 and 12 months.
▪️ Avoid outdated pulpotomy agents with documented cytotoxicity.

📚 References

✔ Camilleri, J. (2014). Tricalcium silicate cements in endodontics. Dental Materials, 30(7), 689–707. https://doi.org/10.1016/j.dental.2014.03.007
✔ Nowicka, A., Lipski, M., Parafiniuk, M., Sporniak-Tutak, K., Lichota, D., Kosierkiewicz, A., ... & Buczkowska-Radlińska, J. (2013). Response of human dental pulp capped with Biodentine and MTA. Journal of Endodontics, 39(6), 743–747. https://doi.org/10.1016/j.joen.2013.01.005
✔ Smaïl-Faugeron, V., Courson, F., Durieux, P., Muller-Bolla, M., Glenny, A. M., & Fron Chabouis, H. (2018). Mineral trioxide aggregate versus calcium hydroxide for pulpotomy in primary molars: A systematic review and meta-analysis. International Journal of Paediatric Dentistry, 28(3), 266–276. https://doi.org/10.1111/ipd.12361
✔ Taha, N. A., & Abdelkhader, S. Z. (2018). Outcome of full pulpotomy using Biodentine in adult patients with symptoms indicative of irreversible pulpitis. International Endodontic Journal, 51(8), 819–828. https://doi.org/10.1111/iej.12902

📌 More Recommended Items

Calcium Hydroxide/Iodoform Paste in Primary Teeth Pulpectomies: Benefits and Clinical Evidence
Pulp Therapy in Pediatric Dentistry: Complete and Updated Guide
Irrigants in Pediatric Pulpectomies: Key Benefits, Properties, and U.S. Commercial Brands

Pharmacological Management According to Post-Extraction Complications

Post-Extraction Complications

Post-extraction complications require targeted pharmacological strategies to prevent pain, infection, and delayed healing. Understanding how to select appropriate medications based on the specific post-extraction complication is essential for safe and predictable outcomes.

📌 Recommended Article :
Dental Article 🔽 How to Prevent Dry Socket After Tooth Extraction: Signs, Prevention, and Treatment Guide ... Preventing dry socket is a key responsibility shared by both dental professionals and patients, involving proper surgical technique, patient education, and targeted pharmacological management.
This article reviews current evidence on the pharmacological management of post-extraction complications, including pain, alveolar osteitis, infection, and soft tissue inflammation.

Advertisement

Common Post-Extraction Complications and Pharmacological Management

1. Pain and Inflammation
Acute pain following extraction is typically nociceptive and inflammatory. Evidence supports the use of nonsteroidal anti-inflammatory drugs (NSAIDs) as first-line therapy due to their superior analgesic and anti-inflammatory effects compared with opioids.

➤ Recommended Pharmacological Management:
▪️ Ibuprofen: 400–600 mg every 6–8 h (max 2400 mg/day).
▪️ Acetaminophen: 500–1000 mg every 6 h (max 3000 mg/day).
Combination therapy (ibuprofen + acetaminophen) has been shown to offer superior analgesia compared with opioid-containing regimens.

📌 Recommended Article :
Dental Article 🔽 Antibiotic Prophylaxis in Pediatric Dentistry: When and How to Use It Safely in 2025 ...Antibiotic prophylaxis in pediatric dentistry is a preventive measure used to avoid serious systemic infections, such as infective endocarditis, in children undergoing dental procedures.
2. Alveolar Osteitis (Dry Socket)
Dry socket results from premature clot loss and localized inflammation. While systemic antibiotics are not recommended, pharmacologic management focuses on local and systemic pain control.

➤ Recommended Pharmacological Management:
▪️ NSAIDs for pain control.
▪️ Topical anesthetic dressings containing eugenol for short-term symptomatic relief.
▪️ Avoid prolonged use of eugenol-based medicaments due to delayed healing risk.

📌 Recommended Article :
PDF 🔽 Manual of extraction techniques in pediatric dentistry - Step by step ... Tooth extraction is a routine treatment in the pediatric dentist's office. This procedure is performed when the tooth presents a deep caries and impossible reconstruction, fracture due to trauma, eruptive problems.
3. Post-Extraction Infection
When a surgical site exhibits suppuration, fever, and spreading erythema, infection is likely present. Antibiotics are indicated only when systemic signs or progressive infection occur, not as routine prophylaxis.

➤ Recommended Antibiotics:
▪️ Amoxicillin 500 mg every 8 h for 5–7 days.
▪️ Amoxicillin-clavulanate 875/125 mg every 12 h for more severe cases.
▪️ Clindamycin 300 mg every 8 h for penicillin-allergic patients.

📌 Recommended Article :
Dental Article 🔽 Anatomical Landmarks in Dental Anesthetic Techniques: A Complete Clinical Review ... This article reviews the main anatomical references for each local anesthetic technique in both adult and pediatric patients, emphasizing clinical precision and anatomical variations.
4. Persistent Swelling or Soft Tissue Inflammation
Post-operative swelling may be associated with trauma or early infection.

➤ Recommended Pharmacological Management:
▪️ NSAIDs as baseline therapy.
▪️ Short course of corticosteroids (e.g., dexamethasone 4 mg single dose, or prednisone 10–20 mg for 1–2 days) may be beneficial in select cases to reduce severe inflammation.

📌 Recommended Article :
Dental Article 🔽 Post-Extraction Complications in Pediatric Dentistry: Prevention and Management of Dry Socket ... This article reviews the etiology, clinical presentation, prevention, and management of dry socket in children, focusing on current pharmacologic and clinical strategies to ensure faster recovery and prevent recurrence.
5. Bleeding-Related Complications
Uncontrolled bleeding is not typically managed pharmacologically, but adjunct medications can help stabilize the site.

➤ Recommended Adjunct Therapies:
▪️ Tranexamic acid mouth rinse (4.8%), particularly in anticoagulated patients.
▪️ Topical hemostatic agents such as oxidized cellulose or gelatin sponges.

📊 Comparative Table: Pharmacological Options by Post-Extraction Complication

Aspect Advantages Limitations
NSAIDs for Pain Control Effective for inflammation and nociceptive pain Contraindicated in gastric disease or renal issues
Antibiotics for Infection Effective for progressive or systemic infections Not indicated for routine post-extraction use

💬 Discussion
Pharmacological management must be tailored to the specific post-extraction complication rather than applied universally. NSAIDs remain the cornerstone for controlling dental extraction pain, with substantial evidence supporting their superiority over opioid regimens. Antibiotics must be used judiciously to limit antimicrobial resistance and adverse effects. Topical medicaments for dry socket offer symptomatic relief but should be applied selectively. Corticosteroids may be useful for severe inflammation but are not routinely required.
Understanding the pathophysiology behind each complication guides medication selection, improving therapeutic outcomes and reducing patient morbidity.

📌 Recommended Article :
Dental Article 🔽 Preventive Measures Before and After Tooth Extraction: Clinical Guidelines for Safe Recovery ... This article presents evidence-based preventive measures before and after extraction to ensure optimal outcomes and patient comfort, highlighting the differences in management between pediatric and adult patients.
🔎 Recommendations
▪️ Use NSAIDs as first-line therapy for pain and inflammation unless contraindicated.
▪️ Reserve systemic antibiotics for cases with clear signs of infection.
▪️ Avoid unnecessary opioid prescriptions.
▪️ Use topical anesthetic dressings for dry socket only when clinically indicated.
▪️ Consider corticosteroids for severe inflammatory swelling on a case-by-case basis.
▪️ Educate patients on warning signs requiring immediate reassessment (fever, worsening pain, spreading swelling).

✍️ Conclusion
Pharmacological management following dental extraction should be individualized based on the complication presented. NSAIDs offer effective first-line analgesia, while systemic antibiotics must be reserved for true infections. Evidence-based selection of analgesics, anti-inflammatory drugs, and adjunct therapies enhances healing and minimizes complications. Adhering to a targeted, complication-specific approach ensures safer and more predictable post-extraction outcomes.

📚 References

✔ American Dental Association. (2020). Evidence-based clinical practice guideline for the pharmacologic management of acute dental pain. Journal of the American Dental Association, 151(11), 891–905. https://doi.org/10.1016/j.adaj.2020.06.006
✔ Beaudoin, F. L., Banerjee, G. N., & Mello, M. J. (2019). State-level opioid prescribing for dental procedures. Journal of the American Dental Association, 150(7), 498–509. https://doi.org/10.1016/j.adaj.2019.02.018
✔ Blum, I. R. (2002). Contemporary views on dry socket (alveolar osteitis): A clinical appraisal of standardization, aetiopathogenesis and management. Journal of Oral and Maxillofacial Surgery, 60(1), 11–17. https://doi.org/10.1053/joms.2002.29825
✔ Halpern, L. R., Dodson, T. B., & Dodson, T. B. (2019). Do corticosteroids reduce postoperative morbidity? Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 128(4), 303–312. https://doi.org/10.1016/j.oooo.2019.04.002
✔ Rogers, S. N., & Patel, M. (2020). Management of post-operative infection in oral surgery. British Journal of Oral and Maxillofacial Surgery, 58(3), 237–243. https://doi.org/10.1016/j.bjoms.2019.11.016

📌 More Recommended Items

Preventing Dental Emergencies in Primary Dentition: Caries, Abscesses and Early Intervention
Analgesic and Antibiotic Recommendations in Pediatric Oral Surgery
Differential Diagnosis of Post-Extraction Conditions: Clinical Guide for Dentists

Oral Manifestations of Systemic Infections in Pediatrics: An Odontological Approach

Oral Manifestations

Pediatric patients often present with oral changes that may reflect underlying systemic infections. Recognizing these oral manifestations of systemic diseases is crucial, as early detection can significantly improve diagnostic accuracy, interdisciplinary coordination, and overall patient outcomes.

📌 Recommended Article :
Dental Article 🔽 Top 5 Signs of Oral Cancer You Shouldn’t Ignore – Early Detection Matters ... This article highlights the five most common early signs of oral cancer that patients and clinicians should recognize for timely diagnosis and effective management.
For pediatric dentists, understanding the systemic–oral health connection is essential for timely referral and appropriate management.

Advertisement

Common Oral Manifestations of Systemic Infections

1. Viral Infections
Viral conditions frequently produce characteristic oral lesions that serve as early clinical indicators.

▪️ Herpes simplex virus (HSV-1): acute gingivostomatitis, multiple vesicles, painful ulcers.
▪️ Varicella-zoster virus: diffuse ulcers, crusted perioral lesions.
▪️ Enteroviruses (herpangina, hand-foot-and-mouth disease): shallow vesicles on the soft palate, tonsillar pillars, or oral mucosa.
These lesions may precede systemic symptoms, making dental assessment a valuable diagnostic tool.

📌 Recommended Article :
PDF 🔽 Mucocele in Pediatric Dentistry: Clinical and pathological characteristics ... Mucocele is a benign lesion that occurs in the oral mucosa and is the product of an alteration in the minor salivary glands. It is recognized as a swelling with mucous content, well circumscribed, and bluish in color.
2. Bacterial Infections
Bacterial pathogens can cause distinct mucosal responses:

▪️ Group A Streptococcus: strawberry tongue, erythema, petechiae.
▪️ Neisseria meningitidis: hemorrhagic mucosal lesions in severe cases.
▪️ Mycobacterium tuberculosis: chronic, indurated oral ulcers.
Dentists must differentiate localized infections from systemic involvement.

📌 Recommended Article :
Dental Article 🔽 Oral Manifestations of STDs: Diagnosis, Signs, and Dental Management ... Sexually transmitted diseases (STDs) remain a global health concern. Several infections, including syphilis, HIV, herpes simplex virus (HSV), gonorrhea, and human papillomavirus (HPV), present oral signs that may be the first indication of systemic illness.
3. Fungal Infections
Oral candidiasis, especially in immunocompromised or antibiotic-treated children, manifests as pseudomembranous plaques, angular cheilitis, or erythematous mucosa. Persistent or recurrent candidiasis may indicate systemic immune deficiency.

📌 Recommended Article :
Dental Article 🔽 Oral Dermatitis Treatment: A Complete Guide for Dentists in 2025 ... Oral dermatitis, often referred to as perioral dermatitis when it involves the skin around the mouth, can extend to intraoral tissues and is sometimes misdiagnosed as other mucosal conditions.
4. Hematologic and Immune-Related Infections
Systemic infections affecting hematologic function often manifest orally:

▪️ Neutropenia: recurrent oral ulcers, severe gingivitis, delayed healing.
▪️ HIV infection: candidiasis, linear gingival erythema, enlarged parotid glands.
▪️ Mononucleosis: palatal petechiae, tonsillar enlargement, lymphadenopathy.
Oral patterns frequently provide early clues before definitive laboratory diagnosis.

📌 Recommended Article :
Dental Article 🔽 Herpangina in Children: Causes, Symptoms, and Treatment of This Viral Infection ... Herpangina is a common viral illness that primarily affects children under the age of five. It is marked by a sudden onset of fever, sore throat, and small ulcers or blisters in the back of the mouth—typically on the soft palate, uvula, and tonsils.
5. COVID-19–Related Oral Findings
Pediatric COVID-19 patients may show erythema, ulcerations, geographic tongue, or mucosal changes associated with Multisystem Inflammatory Syndrome in Children (MIS-C).

📊 Comparative Table: Key Oral Indicators of Systemic Infections in Children

Aspect Advantages Limitations
Oral Lesions as Diagnostic Clues Enable early detection of systemic infections May resemble primary oral diseases
Systemic Assessment Based on Oral Findings Improves interdisciplinary diagnosis and timely referral Requires clinician familiarity with varied presentations

💬 Discussion
The oral cavity serves as both a mirror and a gateway to systemic health. Many systemic infections in children initially manifest as mucosal alterations, ulcerations, or glandular changes detectable during routine dental visits. Pediatric dentists play a critical role in early recognition, aiding physicians in establishing timely diagnoses. Misinterpretation may lead to delayed care or unnecessary treatment; therefore, interprofessional collaboration is vital.
Differentiating between primary oral disease and systemic manifestations requires careful analysis of lesion distribution, duration, systemic signs (fever, malaise, lymphadenopathy), and patient history. Increased awareness leads to improved management pathways and optimized pediatric outcomes.

📌 Recommended Article :
Dental Article 🔽 Cold Sore, Canker Sore, and Oral Thrush: Key Differences You Should Know ... This article explains their main features, clinical presentation, diagnosis, and treatment in both children and adults, providing practical keys for differentiation.
🔎 Recommendations
▪️ Conduct complete extraoral and intraoral examinations in all pediatric visits.
▪️ Document lesion characteristics: size, location, borders, pain, and evolution.
▪️ Evaluate systemic signs and review recent infections, medications, and immunization status.
▪️ Refer promptly when systemic involvement is suspected (fever, rash, lymphadenopathy, recurrent ulcers).
▪️ Educate caregivers about the relationship between systemic infections and oral findings.

✍️ Conclusion
Oral manifestations of systemic infections in children are critical diagnostic indicators that help clinicians detect underlying diseases early. Pediatric dentists are uniquely positioned to observe these signs during routine examinations, contributing to faster diagnosis and comprehensive management. A multidisciplinary approach ensures that children with systemic infections receive timely and effective treatment.

📚 References

✔ Amir, J., & Harel, L. (2007). Oral manifestations of infectious diseases in children. Infectious Disease Clinics of North America, 21(2), 495–521. https://doi.org/10.1016/j.idc.2007.03.007
✔ Arduino, P. G., & Porter, S. R. (2008). Oral and perioral manifestations of viral infections. British Journal of Dermatology, 159(1), 9–20. https://doi.org/10.1111/j.1365-2133.2008.08608.x
✔ Glick, M., & Greenberg, M. S. (2023). Burket’s Oral Medicine (13th ed.). McGraw-Hill.
✔ Petti, S., Lodi, G., & Lilla, M. (2020). Oral lesions in COVID-19 children: A review. Journal of Clinical Pediatric Dentistry, 44(4), 302–308. https://doi.org/10.17796/1053-4628-44.4.10
✔ Shulman, S. T., & Rowley, A. H. (2015). Kawasaki disease clinical features, diagnosis, and management. The Lancet, 386(10000), 1635–1646. https://doi.org/10.1016/S0140-6736(15)00082-7

📌 More Recommended Items

Oral lesions in neonates, children and adolescents. Characteristics, diagnosis and treatment
Oral Manifestations of Systemic Diseases: Updated Clinical Review
Dental Management of Hand-Foot-Mouth Disease: Updated Clinical Guide for Dentists