Modern Alternatives to Calcium Hydroxide Apexification

Management of immature permanent teeth with necrotic pulp has historically relied on calcium hydroxide apexification. However, advances in biomaterials and regenerative biology have significantly changed clinical decision-making.

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Today, regenerative endodontic procedures (REPs) and mineral trioxide aggregate (MTA) apical barriers are increasingly preferred due to their predictable outcomes, reduced treatment time, and superior biological response.

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✅ Traditional Calcium Hydroxide Apexification: Limitations
Calcium hydroxide apexification aims to induce the formation of a calcified apical barrier over several months. Despite its historical importance, multiple disadvantages have been documented:

▪️ Prolonged treatment time, often exceeding 6–18 months
▪️ Increased risk of root fracture due to long-term dentin exposure
▪️ Multiple patient visits, compromising compliance
▪️ Unpredictable apical closure morphology
Long-term calcium hydroxide use weakens radicular dentin, increasing susceptibility to cervical fractures.

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✅ MTA Apical Barriers: A More Predictable Alternative
The introduction of MTA revolutionized apexification by allowing immediate apical barrier formation in one or two visits.

Key advantages include:
▪️ Excellent biocompatibility and bioactivity
▪️ Superior sealing ability
▪️ Reduced treatment duration
▪️ High clinical success rates
MTA apical barriers provide a reliable artificial stop, enabling effective obturation without prolonged intracanal medication.

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✅ Regenerative Endodontics: A Paradigm Shift
Regenerative endodontic procedures aim to restore pulp vitality and promote continued root development, rather than simply closing the apex.

Clinical benefits include:
▪️ Increase in root length and dentin thickness
▪️ Improved fracture resistance
▪️ Potential revascularization of the pulp space
Regenerative endodontics aligns with modern minimally invasive and biologically driven dentistry, especially in young patients.

📊 Comparative Table: Properties of Mineral Trioxide Aggregate (MTA)

Aspect	Advantages	Limitations
Biocompatibility	Excellent tissue tolerance and minimal inflammatory response	May cause mild initial inflammation during setting
Sealing ability	Superior marginal seal even in moist environments	Technique-sensitive placement
Bioactivity	Stimulates hard tissue formation and cementogenesis	Long setting time compared to newer bioceramics
Clinical longevity	High long-term success rates in apexification and perforation repair	Higher cost than traditional materials

💬 Discussion
While calcium hydroxide apexification remains a viable option in selected cases, current evidence strongly favors MTA apical barriers and regenerative techniques. MTA provides predictable outcomes when root development cannot be restored, whereas regenerative endodontics offers true tissue healing and maturation when biological conditions allow.
Case selection, clinician expertise, and patient age play critical roles in choosing the appropriate modality.

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✍️ Conclusion
Traditional calcium hydroxide apexification is being replaced due to its biological limitations and mechanical risks. MTA apical barriers and regenerative endodontics represent evidence-based, modern alternatives that improve clinical outcomes, reduce treatment time, and preserve tooth structure.

🎯 Clinical Recommendations
▪️ Prefer regenerative endodontics in immature teeth with favorable apical anatomy
▪️ Use MTA apical barriers when regeneration is not feasible
▪️ Limit long-term calcium hydroxide use due to fracture risk
▪️ Base treatment decisions on radiographic findings, patient age, and compliance

📚 References

✔ American Association of Endodontists. (2016). Clinical considerations for a regenerative procedure. Journal of Endodontics, 42(3), 505–513. https://doi.org/10.1016/j.joen.2016.01.017
✔ Banchs, F., & Trope, M. (2004). Revascularization of immature permanent teeth with apical periodontitis. Journal of Endodontics, 30(4), 196–200. https://doi.org/10.1097/00004770-200404000-00003
✔ Torabinejad, M., & Parirokh, M. (2010). Mineral trioxide aggregate: A comprehensive literature review—Part II. Journal of Endodontics, 36(2), 190–202. https://doi.org/10.1016/j.joen.2009.09.010
✔ Andreasen, J. O., Farik, B., & Munksgaard, E. C. (2002). Long-term calcium hydroxide as a root canal dressing may increase risk of root fracture. Dental Traumatology, 18(3), 134–137. https://doi.org/10.1034/j.1600-9657.2002.00097.x

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Antibiotic Management in Pediatric Dental Emergencies: Clinical Indications, Risks, and Best Practices

Pediatric dental emergencies are common in clinical practice and often involve pain, infection, or trauma. While antibiotics are frequently prescribed, their inappropriate use contributes to antimicrobial resistance and adverse effects in children.

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Dental Article 🔽 Antibiotics in Pediatric Dentistry: When They Are Needed and When They Are Not ... Antibiotics should only be prescribed when there is systemic involvement, risk of dissemination, or when dental treatment alone is insufficient.

Understanding when antibiotics are truly indicated and selecting the correct agent is essential for safe and effective management in pediatric dentistry.

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✅ Etiology of Dental Emergencies in Children
Dental emergencies in children usually arise from:

▪️ Untreated dental caries
▪️ Pulpal and periapical infections
▪️ Traumatic dental injuries
▪️ Periodontal or soft tissue infections
▪️ Systemic spread of odontogenic infections
👉 Most pediatric dental emergencies are inflammatory rather than infectious and do not require antibiotics.

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✅ Common Pediatric Dental Emergencies and Antibiotic Use

1. Acute Apical Abscess with Systemic Involvement
➤ Signs and Symptoms
▪️ Facial swelling
▪️ Fever
▪️ Malaise
▪️ Lymphadenopathy
▪️ Trismus (in severe cases)
➤ Treatment
▪️ Drainage and removal of infection source
▪️ Antibiotics indicated only if systemic signs are present
➤ Common Antibiotics
▪️ Amoxicillin
▪️ Amoxicillin–clavulanic acid (severe cases)
▪️ Clindamycin (penicillin allergy)

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2. Cellulitis of Odontogenic Origin
➤ Signs and Symptoms
▪️ Diffuse facial swelling
▪️ Fever
▪️ Rapid progression
▪️ Difficulty swallowing or breathing (red flag)
➤ Treatment
▪️ Immediate antibiotic therapy
▪️ Hospital referral if airway compromise is suspected
➤ Common Antibiotics
▪️ Amoxicillin–clavulanic acid
▪️ Clindamycin (penicillin allergy)

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3. Dental Trauma (Avulsion, Luxation)
➤ Signs and Symptoms
▪️ Tooth displacement or loss
▪️ Bleeding
▪️ Soft tissue injury
➤ Treatment
▪️ Repositioning or replantation
▪️ Antibiotics only in specific cases (avulsion, contaminated wounds)
➤ Common Antibiotics
▪️ Amoxicillin
▪️ Doxycycline (limited pediatric use, age-dependent)

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4. Pericoronitis (Rare but Possible in Adolescents)
➤ Signs and Symptoms
▪️ Pain around erupting molars
▪️ Gingival inflammation
▪️ Limited mouth opening
➤ Treatment
▪️ Local irrigation
▪️ Antibiotics only if systemic involvement exists
➤ Common Antibiotics
▪️ Amoxicillin
▪️ Metronidazole (combined therapy in selected cases)

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5. Necrotizing Periodontal Infections
➤ Signs and Symptoms
▪️ Severe gingival pain
▪️ Ulceration
▪️ Fetid odor
▪️ Fever
➤ Treatment
▪️ Mechanical debridement
▪️ Systemic antibiotics when systemic signs are present
➤ Common Antibiotics
▪️ Metronidazole
▪️ Amoxicillin (combination therapy)

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✅ Key Principles of Antibiotic Use in Pediatric Dentistry

▪️ Antibiotics are adjuncts, not substitutes, for dental treatment
▪️ Local intervention is the primary therapy
▪️ Weight-based dosing is mandatory
▪️ Shortest effective duration should be prescribed
👉 Pain alone is never an indication for antibiotic therapy.

💬 Discussion
Despite clear clinical guidelines, antibiotics remain overprescribed in pediatric dental emergencies. Conditions such as irreversible pulpitis or localized abscesses without systemic involvement do not benefit from antibiotic therapy.
Educating clinicians and caregivers is essential to reduce misuse, prevent resistance, and protect pediatric patients from unnecessary drug exposure.

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🎯 Clinical Recommendations
▪️ Prescribe antibiotics only when systemic signs are present
▪️ Always perform definitive dental treatment
▪️ Use narrow-spectrum antibiotics whenever possible
▪️ Adjust dosage according to the child’s weight
▪️ Reassess the patient within 48–72 hours

✍️ Conclusion
Antibiotic management in pediatric dental emergencies must be evidence-based and diagnosis-driven. Appropriate use improves outcomes, reduces complications, and limits antimicrobial resistance. Pediatric dentists play a critical role in promoting responsible antibiotic stewardship.

📚 References

✔ American Academy of Pediatric Dentistry. (2023). Use of antibiotic therapy for pediatric dental patients. Pediatric Dentistry, 45(6), 421–428.
✔ Cope, A. L., Francis, N. A., Wood, F., & Chestnutt, I. G. (2014). Antibiotic prescribing in UK general dental practice. British Dental Journal, 217(11), 651–655.
✔ Fouad, A. F., et al. (2020). Antibiotics and endodontics: A review. Journal of Endodontics, 46(6), 762–774.
✔ Robertson, D., & Smith, A. J. (2009). The microbiology of the acute dental abscess. Journal of Medical Microbiology, 58(2), 155–162.
✔ World Health Organization. (2022). Global antimicrobial resistance and use surveillance system (GLASS) report.

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Oral Health Consequences of Asthma in Children and Adolescents: Dental Risks and Preventive Strategies

Asthma is one of the most common chronic diseases in children and adolescents, and its impact extends beyond the respiratory system. Growing evidence shows that asthma and its pharmacological treatment can negatively affect oral and dental health, increasing the risk of caries, erosion, periodontal inflammation, and mucosal alterations.

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Understanding these oral health consequences of pediatric asthma is essential for early prevention and effective interdisciplinary management.

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✅ Etiology: Why Does Asthma Affect Oral Health?
The oral consequences associated with asthma are multifactorial and include:

▪️ Chronic mouth breathing, leading to reduced salivary flow
▪️ Use of inhaled medications, especially corticosteroids and β2-agonists
▪️ Lower salivary pH and buffering capacity
▪️ Alteration of oral microbiota
▪️ Increased plaque accumulation
👉 Asthma-related xerostomia is a key factor in oral disease development.

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✅ Main Oral and Dental Consequences of Asthma

1. Dental Caries
Children with asthma have a higher prevalence of dental caries, mainly due to:

▪️ Reduced salivary flow
▪️ Increased consumption of sugary beverages to relieve dry mouth
▪️ Acidic formulations of inhaled medications
Asthmatic children are at increased risk of early enamel demineralization.

2. Dental Erosion

▪️ Frequent exposure to acidic inhalers
▪️ Reduced salivary neutralization
▪️ Possible association with gastroesophageal reflux, common in asthmatic patients
Dental erosion may affect both primary and permanent dentition.

3. Gingivitis and Periodontal Inflammation

▪️ Increased plaque retention due to dry oral tissues
▪️ Altered immune response
▪️ Inflammatory effects of corticosteroids
Asthma has been linked to higher gingival inflammation indices in adolescents.

4. Oral Candidiasis

▪️ Common in children using inhaled corticosteroids without spacers
▪️ Favored by immunosuppressive effects and reduced saliva

5. Malocclusion and Craniofacial Changes
Chronic mouth breathing may contribute to:

▪️ Anterior open bite
▪️ Posterior crossbite
▪️ Narrow maxillary arch

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✅ Clinical Signs and Symptoms
Common findings include:

▪️ Dry mouth (xerostomia)
▪️ White spot lesions
▪️ Increased caries activity
▪️ Gingival redness and bleeding
▪️ Burning mouth sensation
▪️ Fungal plaques on oral mucosa

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✅ Preventive Measures
Effective prevention requires a combined medical and dental approach:

▪️ Use of spacers with inhalers
▪️ Rinsing the mouth with water after inhaler use
▪️ Daily fluoride toothpaste (age-appropriate concentration)
▪️ Topical fluoride applications
▪️ Saliva-stimulating strategies
▪️ Dietary counseling to reduce sugar intake
👉 Simple preventive habits significantly reduce oral complications in asthmatic children.

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✅ Dental Treatment Considerations

▪️ Schedule dental appointments during periods of asthma control
▪️ Avoid known asthma triggers in the dental office
▪️ Monitor caries risk closely
▪️ Use minimally invasive restorative approaches
▪️ Collaborate with pediatricians and pulmonologists when needed

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💬 Discussion
Asthma in children and adolescents presents a significant but often underestimated risk factor for oral disease. The combination of respiratory alterations, medication effects, and behavioral factors contributes to an environment favorable to dental pathology.
Early identification and preventive strategies can dramatically reduce long-term oral complications.

🎯 Clinical Recommendations
▪️ Include asthma status in dental risk assessment
▪️ Educate parents and caregivers on inhaler-related oral risks
▪️ Reinforce preventive dentistry protocols
▪️ Ensure regular dental follow-ups
▪️ Promote interdisciplinary care

✍️ Conclusion
Asthma is not only a respiratory condition—it also affects oral health. Children and adolescents with asthma are at increased risk for caries, erosion, gingivitis, and mucosal infections. With proper preventive measures, patient education, and coordinated care, these oral complications can be effectively prevented and managed.

📚 References

✔ Alavaikko, S., Jaakkola, M. S., & Jaakkola, J. J. K. (2011). Asthma and caries: A systematic review and meta-analysis. American Journal of Epidemiology, 174(6), 631–641.
✔ Godara, N., Godara, R., & Khullar, M. (2011). Impact of inhalation therapy on oral health. Lung India, 28(4), 272–275.
✔ Ryberg, M., Möller, C., & Ericson, T. (1991). Saliva composition and caries development in asthmatic patients. Journal of Dental Research, 70(3), 479–483.
✔ Thomas, M. S., & Parolia, A. (2010). Asthma and oral health: A review. Australian Dental Journal, 55(2), 128–133.
✔ Wogelius, P., et al. (2004). Dental caries and asthma in children. Community Dentistry and Oral Epidemiology, 32(5), 347–353.

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Hairy Tongue in Children: Etiology, Clinical Features, and Treatment

Hairy tongue (lingua villosa) in pediatric patients is an uncommon but benign oral condition characterized by elongation and delayed desquamation of the filiform papillae on the dorsal surface of the tongue.

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Although more frequently reported in adults, children may develop hairy tongue, often associated with antibiotic use, poor oral hygiene, or systemic conditions. Early recognition is essential to avoid misdiagnosis and unnecessary treatment.

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✅ Etiology in Pediatric Patients
In children, hairy tongue is primarily caused by impaired keratin shedding, leading to accumulation of keratin on the filiform papillae.

Common pediatric-related etiological factors include:
▪️ Recent or prolonged antibiotic therapy
▪️ Inadequate oral hygiene habits
▪️ Mouth breathing
▪️ Xerostomia related to medications
▪️ Liquid or soft diets
▪️ Use of antiseptic mouth rinses without supervision
Importantly, hairy tongue is not an infectious disease and does not represent a systemic pathology by itself.

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✅ Clinical Signs and Symptoms
Pediatric patients are often asymptomatic, and the condition is usually detected during routine dental examination.

Typical clinical features include:
▪️ Hair-like projections on the dorsal surface of the tongue
▪️ Color changes (white, yellow, brown, or black)
▪️ Mild halitosis
▪️ Occasional gag reflex or foreign body sensation
Pain, ulceration, or bleeding are not characteristic findings.

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✅ Diagnosis in Children
Diagnosis is purely clinical and based on visual examination. The elongated filiform papillae are easily distinguished from other oral conditions.

Differential diagnosis should include:
▪️ Oral candidiasis (especially after antibiotics)
▪️ Geographic tongue
▪️ Oral hairy leukoplakia (rare in immunocompetent children)
▪️ Biopsy or laboratory tests are rarely required.

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✅ Treatment and Management in Odontopediatrics
Management focuses on behavioral and hygienic measures, rather than medication.

Recommended pediatric management includes:
▪️ Gentle tongue brushing or scraping
▪️ Reinforcement of age-appropriate oral hygiene education
▪️ Discontinuation of unnecessary mouth rinses
▪️ Review of recent antibiotic use
▪️ Adequate hydration
Antifungal or antibiotic treatment is not indicated unless another condition is confirmed.

📊 Comparative Table: Pediatric Hairy Tongue – Clinical Characteristics

Aspect	Advantages	Limitations
Clinical Appearance	Easily identifiable during oral examination	May alarm parents due to dark coloration
Etiology	Often reversible and related to modifiable factors	Sometimes linked to necessary antibiotic therapy
Treatment Approach	Non-invasive and conservative	Requires cooperation from child and caregivers
Prognosis	Excellent with complete resolution	Possible recurrence if habits persist

💬 Discussion
In pediatric dentistry, hairy tongue is frequently underrecognized or misdiagnosed as oral candidiasis, leading to unnecessary antifungal prescriptions. Understanding its benign and self-limiting nature allows clinicians to focus on education, reassurance, and preventive strategies, which are fundamental principles in odontopediatrics.

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🎯 Clinical Recommendations
▪️ Reassure parents about the benign nature of the condition
▪️ Avoid prescribing antifungals without clear clinical indication
▪️ Reinforce daily tongue hygiene as part of oral care routines
▪️ Monitor children receiving prolonged antibiotic therapy
▪️ Schedule follow-up visits to confirm resolution

✍️ Conclusion
Hairy tongue in children is a benign, reversible condition associated with hygiene and medication-related factors. Early diagnosis, conservative management, and parental education ensure favorable outcomes without invasive interventions. Odontopediatricians play a key role in preventing overtreatment and promoting oral health awareness.

📚 References

✔ Gurvits, G. E., & Tan, A. (2014). Black hairy tongue syndrome. World Journal of Gastroenterology, 20(31), 10845–10850. https://doi.org/10.3748/wjg.v20.i31.10845
✔ Neville, B. W., Damm, D. D., Allen, C. M., & Chi, A. C. (2016). Oral and maxillofacial pathology (4th ed.). Elsevier.
✔ Houghton, J., & McCullough, M. J. (2017). Oral conditions associated with antibiotic use. Australian Dental Journal, 62(3), 309–315. https://doi.org/10.1111/adj.12524

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Dental Prostheses Without Proper Care Can Lead to Serious Oral Damage

Dental prostheses are designed to restore function, aesthetics, and oral health, but when they are poorly fitted or inadequately maintained, they may become a significant source of chronic trauma and oral disease.

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Both fixed and removable dental prostheses can lead to painful, inflammatory, and potentially serious lesions affecting soft and hard tissues.

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Understanding which lesions are associated with each type of prosthesis is essential for early diagnosis, prevention, and appropriate clinical management.

✅ Etiology: Why Do Dental Prostheses Cause Oral Lesions?
The main etiological factors include:

▪️ Poor marginal adaptation
▪️ Overcontoured prosthetic surfaces
▪️ Incorrect occlusal contacts
▪️ Prosthetic instability or overextension
▪️ Inadequate oral hygiene
▪️ Long-term use without professional follow-up
👉 Chronic mechanical irritation remains the primary mechanism leading to tissue damage.

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✅ Lesions Caused by Poorly Fitted Fixed Dental Prostheses
Poorly adapted crowns, bridges, and implant-supported restorations can cause localized but progressive tissue damage.

Common lesions include:
▪️ Traumatic gingivitis caused by overhanging margins
▪️ Chronic periodontal inflammation due to plaque accumulation
▪️ Violation of the biologic width, leading to persistent bleeding and attachment loss
▪️ Gingival recession associated with improper emergence profiles
▪️ Secondary caries at restoration margins
▪️ Periapical lesions related to occlusal overload
▪️ Oral ulcerations caused by sharp or overcontoured prosthetic edges
👉 Poor marginal fit is a major risk factor for biological failure of fixed prostheses.

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✅ Lesions Caused by Poorly Fitted Removable or Complete Dentures
Ill-fitting removable partial dentures and complete dentures affect larger mucosal areas and are strongly associated with chronic inflammatory conditions.

Common lesions include:
▪️ Denture stomatitis, characterized by erythematous palatal mucosa
▪️ Traumatic ulcers due to instability or overextension
▪️ Epulis fissuratum caused by chronic flange irritation
▪️ Inflammatory papillary hyperplasia, especially in long-term denture wearers
▪️ Angular cheilitis, often related to reduced vertical dimension
▪️ Residual ridge resorption due to uneven force distribution
▪️ Denture-associated oral candidiasis, particularly in elderly or immunocompromised patients
👉 Continuous use of ill-fitting dentures significantly increases mucosal pathology risk.

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✅ Clinical Signs and Symptoms
Patients with prosthesis-related lesions may present with:

▪️ Persistent oral pain or discomfort
▪️ Erythema and swelling
▪️ Ulcerations that do not heal
▪️ Bleeding during brushing
▪️ Burning mouth sensation
▪️ Difficulty chewing or speaking
Early recognition is key to preventing progression.

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✅ Diagnosis
Diagnosis is based on:

▪️ Detailed clinical examination
▪️ Evaluation of prosthesis fit, contours, and occlusion
▪️ Assessment of oral hygiene status
▪️ In selected cases, biopsy to rule out dysplastic or malignant lesions

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✅ Treatment and Clinical Management
Management depends on lesion type and severity and may include:

▪️ Prosthesis adjustment or replacement
▪️ Removal of traumatic factors
▪️ Improvement of oral hygiene protocols
▪️ Topical antifungal therapy for denture-related candidiasis
▪️ Anti-inflammatory or protective agents
▪️ Temporary discontinuation of denture use in severe cases
Treating the lesion without correcting the prosthesis will lead to recurrence.

💬 Discussion
Poorly fitted dental prostheses remain a preventable cause of oral lesions. Fixed prostheses tend to cause localized periodontal and biological complications, while removable dentures are more frequently associated with extensive mucosal inflammation and chronic trauma.
Routine follow-up and patient education are essential to reduce long-term complications.

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Video 🔽 Risk of gum disease for smokers ... We all know the effects of tobacco on our body, none positive by the way, and the oral cavity does not escape its harmful effects. It has been shown that smoking increases the risk of periodontitis and also affects the response to periodontal therapies.

🎯 Clinical Recommendations
▪️ Always evaluate prosthesis fit during recall visits
▪️ Educate patients on proper prosthesis hygiene
▪️ Replace or reline dentures periodically
▪️ Avoid prolonged use of unstable or damaged prostheses
▪️ Investigate non-healing lesions promptly

✍️ Conclusion
Dental prostheses should improve oral health—not compromise it. Poorly fitted fixed and removable prostheses can cause serious oral lesions if not properly designed, monitored, and maintained. Early intervention and regular professional care are essential to prevent long-term damage.

📚 References

✔ Budtz-Jørgensen, E. (1990). Oral mucosal lesions associated with the wearing of removable dentures. Journal of Oral Pathology & Medicine, 19(2), 65–70.
✔ Felton, D. (2016). Edentulism and comorbid factors. Journal of Prosthodontics, 25(Suppl 1), S2–S20.
✔ Goodacre, C. J., Bernal, G., Rungcharassaeng, K., & Kan, J. Y. (2003). Clinical complications in fixed prosthodontics. The Journal of Prosthetic Dentistry, 90(1), 31–41.
✔ Gendreau, L., & Loewy, Z. G. (2011). Epidemiology and etiology of denture stomatitis. Journal of Prosthodontics, 20(4), 251–260.
✔ Lang, N. P., & Berglundh, T. (2011). Periimplant diseases. Journal of Clinical Periodontology, 38(Suppl 11), 178–181.

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