Bednar's aphthae are traumatic oral ulcers that occur primarily in newborns and young infants. They typically develop on the posterior region of the hard palate, near the junction with the soft palate, as a result of repetitive mechanical irritation.
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Understanding their characteristic location, clinical presentation, and underlying mechanism is essential for establishing an accurate diagnosis and avoiding unnecessary treatment.
✅ Etiology and Pathophysiology
The exact pathogenesis of Bednar's aphthae remains incompletely understood. However, mechanical trauma and repetitive pressure on the palatal mucosa are considered the principal contributing factors.
Commonly associated factors include:
▪️ Bottle-feeding: Repeated contact between the nipple and posterior palate.
▪️ Breastfeeding: Mechanical pressure during sucking.
▪️ Incorrect feeding position: Feeding the infant in a horizontal position may increase palatal pressure.
▪️ Pacifier use: Repetitive friction or pressure against the palatal tissues.
▪️ Nipple characteristics: Inappropriate nipple design or flow may contribute to feeding-related trauma.
The neonatal oral mucosa is particularly susceptible to mechanical injury. Repetitive irritation can result in localized epithelial damage and ulcer formation.
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Bednar's aphthae have characteristic clinical features that facilitate diagnosis.
▪️ Location: Posterior hard palate, particularly near the junction with the soft palate.
▪️ Appearance: Superficial, shallow ulcerations with whitish or yellowish surfaces.
▪️ Shape: Typically oval or round, sometimes linear.
▪️ Distribution: Frequently bilateral and symmetrical, although unilateral presentations may occur.
▪️ Surrounding tissue: May exhibit a slightly erythematous margin.
▪️ Symptoms: Often asymptomatic, but some infants experience irritability, prolonged feeding time, or reduced milk intake.
Clinical observations reported by Nam et al. (2016) demonstrated that feeding difficulties were common, although some lesions were discovered incidentally during routine examinations.
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The diagnosis of Bednar's aphthae is primarily clinical, based on the infant's age, characteristic ulcer location, lesion morphology, and feeding history.
A comprehensive oral examination should evaluate:
▪️ Location, number, symmetry, and appearance of the ulcers.
▪️ Presence of erythema, bleeding, or additional oral lesions.
▪️ Feeding techniques, bottle nipple characteristics, and pacifier use.
▪️ Associated symptoms, including fever and feeding intolerance.
Laboratory investigations and biopsies are not routinely indicated when the clinical presentation is characteristic and the infant is otherwise healthy.
However, atypical lesions or systemic symptoms require further evaluation to exclude infectious or other pathological conditions.
✅ Differential Diagnosis
Several neonatal oral conditions may resemble Bednar's aphthae. Accurate differentiation is essential to prevent unnecessary treatment.
| Condition | Characteristic Clinical Findings |
|---|---|
| Bednar's aphthae | Superficial, frequently symmetrical ulcers at the posterior hard palate. |
| Oral candidiasis | White plaques on the tongue, buccal mucosa, or palate that are not easily removed. |
| Neonatal herpes simplex | Vesicles progressing to multiple ulcers, often accompanied by systemic symptoms. |
| Traumatic oral ulcer | Localized ulceration associated with identifiable mechanical injury. |
| Epstein pearls | Small, white or yellow keratin-filled cysts along the palatal midline; non-ulcerative. |
| Herpangina | Vesicular and ulcerative lesions predominantly involving the soft palate and posterior oropharynx, often with fever. |
✅ Management and Treatment Bednar's aphthae are benign and generally resolve spontaneously. Treatment focuses on eliminating mechanical irritation rather than prescribing medication.
The following measures are recommended:
1. Correct feeding position: Encourage a semi-upright feeding position to reduce repetitive pressure on the posterior palate.
2. Evaluate bottle-feeding technique: Assess nipple flow, design, and positioning. Correct any feeding difficulties without arbitrarily enlarging the nipple opening.
3. Assess pacifier use: Identify whether the pacifier contributes to repetitive palatal irritation and modify its use when necessary.
4. Monitor oral healing: Reassess the lesions and feeding behavior to ensure progressive improvement.
5. Maintain adequate nutrition: Monitor milk intake, hydration, and weight gain when feeding difficulties are present.
Pharmacological treatment is generally unnecessary. Antibiotics, antifungals, and topical corticosteroids are not indicated for uncomplicated Bednar's aphthae.
Topical anesthetics should not be routinely applied to neonatal oral ulcers because of potential adverse effects.
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The prognosis of Bednar's aphthae is excellent. Most lesions resolve spontaneously after eliminating the contributing mechanical factors.
Clinical observations indicate that healing generally occurs within one to four weeks, although the recovery period varies according to lesion severity and continued irritation.
Persistent, enlarging, recurrent, or atypical ulcers require reassessment to exclude other conditions.
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Bednar's aphthae represent an important diagnostic consideration in neonatal and infant oral pathology. Despite their benign nature, these lesions may be overlooked or mistaken for infectious ulcerative conditions.
The study by Nebgen et al. (2010), involving 1,494 neonates, identified Bednar's aphthae in 15.8% of examined infants whose entire palate could be visualized. This finding suggests that the condition may be more frequent than commonly recognized.
Furthermore, Nam et al. (2016) demonstrated that correcting feeding position and technique was associated with lesion resolution in their retrospective series of 16 infants.
Although the available evidence is limited by relatively small clinical studies and observational designs, findings consistently support mechanical irritation as an important contributing factor.
Early recognition and appropriate parental education are therefore central to conservative management, reducing unnecessary diagnostic procedures and medication use.
✍️ Conclusion
Bednar's aphthae are benign traumatic ulcers affecting the posterior palatal mucosa of newborns and infants. Their characteristic clinical distribution, association with feeding-related mechanical pressure, and spontaneous healing facilitate clinical recognition.
Management should prioritize identifying and eliminating the source of irritation, supporting adequate feeding, and monitoring healing. Recognition of these lesions is essential for avoiding unnecessary pharmacological interventions and ensuring appropriate neonatal oral care.
🎯 Clinical Recommendations
For pediatric dentists and healthcare professionals, the following recommendations support practical clinical management:
▪️ Prioritize clinical diagnosis: Consider Bednar's aphthae when symmetrical posterior palatal ulcers are identified in an otherwise healthy infant.
▪️ Evaluate feeding mechanics: Examine feeding position and the interaction between the nipple or pacifier and palatal tissues.
▪️ Avoid unnecessary medication: Do not prescribe antimicrobial agents for uncomplicated traumatic lesions.
▪️ Establish follow-up: Confirm lesion regression and adequate feeding. Investigate promptly if systemic symptoms, dehydration, or atypical progression occurs.
📚 References
✔ Nam, S. W., Ahn, S. H., Shin, S. M., & Jeong, G. (2016). Clinical features of Bednar's aphthae in infants. Korean Journal of Pediatrics, 59(1), 30–34. https://doi.org/10.3345/kjp.2016.59.1.30
✔ Nebgen, S., Kasper, H. U., Schäfer, D., Christ, H., & Roth, B. (2010). Bednar's aphthae in neonates: Incidence and associated factors. Neonatology, 98(2), 208–211. https://doi.org/10.1159/000285523
✔ Pedra, C., Terra, C. M., Ejzenberg, B., Baldacci, E. R., & Okay, Y. (1996). Oral palatine ulcers of a traumatic nature in infants: Bednar's aphthae. International Journal of Pediatric Otorhinolaryngology, 35(1), 39–49. https://doi.org/10.1016/0165-5876(95)01282-6
✔ Chaudhry, A. (2021). Infantile Bednar's aphthae. Journal of Paediatrics and Child Health, 57(10), 1717. https://doi.org/10.1111/jpc.1_15383
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