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jueves, 10 de septiembre de 2026

Skeletal vs Dental Malocclusion: Key Differences and Treatment Planning

Dental Malocclusion

Skeletal and dental malocclusions may produce similar occlusal findings but require fundamentally different diagnostic approaches and treatment strategies.

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A Class II or Class III molar relationship, increased overjet, deep bite, or anterior crossbite does not by itself establish whether the primary problem originates from the jaws or the dentition.

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The distinction between skeletal discrepancy and dental compensation is particularly important when treatment may involve growth modification, orthodontic camouflage, temporary skeletal anchorage, or orthognathic surgery.
Accurate diagnosis therefore requires integration of facial examination, dental relationships, skeletal measurements, incisor inclination, and soft-tissue characteristics rather than reliance on a single cephalometric parameter.

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🔹 What Is a Dental Malocclusion?
A dental malocclusion primarily results from abnormal tooth position, inclination, rotation, crowding, spacing, or dental arch relationships despite relatively acceptable underlying skeletal relationships.

Examples include:
▪️ Dental crowding or spacing
▪️ Rotated or displaced teeth
▪️ Dental midline discrepancies
▪️ Dentoalveolar Class II or Class III relationships
▪️ Localized crossbites caused predominantly by tooth position
▪️ Incisor inclination abnormalities
In these situations, orthodontic tooth movement can often correct the malocclusion without substantially altering the underlying skeletal relationship.

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🔹 What Is a Skeletal Malocclusion?
A skeletal malocclusion results primarily from an anteroposterior, vertical, or transverse discrepancy between the maxilla, mandible, or both.

Common patterns include:
▪️ Skeletal Class II: mandibular deficiency, maxillary excess, or a combination
▪️ Skeletal Class III: mandibular excess, maxillary deficiency, or a combination
▪️ Vertical skeletal discrepancies: hyperdivergent or hypodivergent facial patterns, anterior open bite, or excessive lower anterior facial height
▪️ Transverse skeletal discrepancies: maxillary or mandibular basal arch-width discrepancies
▪️ Facial asymmetries involving the underlying skeletal structures
Importantly, the dental arches may partially compensate for the skeletal discrepancy, potentially making the underlying skeletal problem less obvious clinically.
Diagnostic Feature Dental Malocclusion Skeletal Malocclusion
Primary origin Tooth position or dentoalveolar relationship Maxillary or mandibular skeletal discrepancy
Facial profile Usually relatively balanced May show sagittal, vertical, or transverse disharmony
Incisor position Abnormal position may be the primary problem Frequently compensatory to the skeletal discrepancy
Occlusal relationship Often localized or primarily dentoalveolar Often reflects a broader jaw discrepancy
Cephalometric findings Skeletal bases may be relatively balanced Sagittal, vertical, or transverse skeletal discrepancy may be evident
Treatment Primarily orthodontic tooth movement Growth modification, orthodontic camouflage, or orthognathic treatment depending on severity and growth status
Main limitation Biological limits of dental movement Biological limits of dental compensation
🔹 How to Differentiate Skeletal and Dental Components

1. Evaluate the Facial Pattern
Extraoral examination should precede interpretation of individual dental relationships. Assessment should include:

▪️ Facial symmetry
▪️ Profile convexity or concavity
▪️ Lower anterior facial height
▪️ Lip competence and incisor display
▪️ Chin projection
▪️ Vertical proportions
▪️ Smile and soft-tissue balance
Soft-tissue evaluation is particularly relevant because a technically acceptable occlusion may still be associated with an unfavorable facial profile when a significant skeletal discrepancy remains untreated.

2. Analyze the Dental Compensation
Incisor inclination is a critical diagnostic clue. In skeletal Class II and Class III patterns, the incisors may compensate for the underlying jaw discrepancy.

For example, a patient with skeletal Class III may present with:
▪️ Proclined maxillary incisors
▪️ Retroclined mandibular incisors
▪️ Relatively acceptable overjet despite a significant skeletal discrepancy
These compensations can mask the true severity of the skeletal problem. Conversely, removing the compensations during presurgical orthodontics may temporarily make the malocclusion appear worse while revealing the actual skeletal discrepancy.

3. Use Cephalometric Analysis as Part of the Diagnosis
Cephalometric analysis can help quantify the relationship between the maxilla, mandible, and dentition. Depending on the clinical problem, useful parameters may include:

▪️ SNA and SNB
▪️ ANB
▪️ Wits appraisal
▪️ Mandibular plane measurements
▪️ Upper and lower incisor inclinations
▪️ Interincisal angle
▪️ Vertical facial proportions
However, these measurements should not be interpreted independently. Reference planes, facial morphology, dental compensation, and individual anatomical variation can influence their diagnostic meaning.
Evidence also indicates that cephalometric radiographs are not universally necessary for every orthodontic patient; their value increases when a skeletal discrepancy, asymmetry, significant vertical problem, or potential surgical treatment requires clarification.

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🔹 Treatment Planning: Dental vs Skeletal Problems
Treatment planning should begin by determining where the discrepancy originates and what the biological limits of correction are.

1. Dental Malocclusion
When the skeletal bases are reasonably harmonious, treatment may focus on:
▪️ Alignment and leveling
▪️ Space management
▪️ Arch coordination
▪️ Incisor inclination
▪️ Correction of rotations
▪️ Interarch dental relationships
The treatment objective is primarily to establish a stable and functional dentition within the existing skeletal framework.

2. Skeletal Malocclusion
When the discrepancy is skeletal, treatment options depend on age, growth potential, severity, facial aesthetics, periodontal limitations, and patient-specific objectives.

Possible approaches include:
Growing patients
▪️ Growth modification when appropriate
▪️ Orthodontic correction of associated dental compensation
▪️ Dentofacial orthopedic approaches for selected sagittal or transverse discrepancies

Non-growing patients
▪️ Orthodontic camouflage for carefully selected mild-to-moderate discrepancies
▪️ Temporary skeletal anchorage when additional dentoalveolar control is required
▪️ Orthodontic-orthognathic treatment when the skeletal discrepancy exceeds the limits of dental compensation
Orthodontic camouflage can be effective in selected borderline cases, but it does not correct the underlying jaw discrepancy. Recent evidence continues to emphasize that treatment selection must consider the magnitude of the skeletal discrepancy, dental compensation, facial aesthetics, function, and the patient's treatment objectives.

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🔹 When Is Orthognathic Surgery Considered?
Orthognathic surgery becomes relevant when the skeletal discrepancy cannot be predictably corrected by orthodontic tooth movement without unacceptable dental, periodontal, functional, or facial consequences.

Important considerations include:
▪️ Magnitude of the skeletal discrepancy
▪️ Facial profile and soft-tissue imbalance
▪️ Incisor position relative to the basal bone
▪️ Available periodontal envelope
▪️ Vertical and transverse skeletal discrepancies
▪️ Stability of potential dental compensation
▪️ Growth status
▪️ Functional limitations
▪️ Patient expectations
In surgical cases, presurgical orthodontics is generally directed toward decompensating the dentition and positioning the teeth appropriately relative to their skeletal bases, allowing the surgical correction to address the underlying jaw discrepancy.

🔹 Skeletal vs Dental Malocclusion: A Practical Diagnostic Framework
Diagnostic Question Clinical Interpretation Treatment Implication
Are the maxillary and mandibular bases reasonably coordinated? Suggests a predominantly dental problem. Orthodontic tooth movement may be sufficient.
Is there a significant facial skeletal discrepancy? Suggests a skeletal component. Assess growth modification, camouflage, or surgery.
Are incisors markedly compensated? Dental compensation may be masking the skeletal discrepancy. Evaluate periodontal limits and potential for decompensation.
Can the discrepancy be corrected within the dental envelope? Determines the feasibility of orthodontic compensation. If limits are exceeded, surgical correction should be evaluated.
💬 Discussion
The distinction between skeletal and dental malocclusion is not simply a classification exercise; it determines the biological and therapeutic boundaries of orthodontic treatment. Dental compensation can produce an acceptable occlusal relationship while concealing a clinically important skeletal discrepancy.
This is particularly relevant in borderline Class II and Class III cases. Systematic reviews indicate that camouflage and surgical treatment produce different dentoskeletal effects, with surgery providing greater correction of the underlying skeletal relationship, whereas camouflage relies primarily on dental compensation.
Recent evidence also reinforces that there is no single numerical cephalometric threshold that independently determines treatment modality. Contemporary treatment planning should integrate skeletal measurements with facial aesthetics, dental compensation, periodontal boundaries, function, growth status, and the feasibility of achieving stable results.

✍️ Conclusion
Skeletal vs dental malocclusion should be differentiated through an integrated assessment of facial morphology, dental relationships, skeletal bases, incisor compensation, and soft tissues. A dental discrepancy may often be corrected through conventional orthodontic mechanics, whereas a significant skeletal discrepancy may require growth modification, carefully controlled camouflage, or orthognathic surgery.
The central treatment-planning principle is to determine whether the observed occlusion represents a primary dental problem or a dental compensation masking an underlying skeletal discrepancy.

💡 Clinical Pearls
▪️ Do not diagnose a skeletal discrepancy from molar or canine relationships alone.
▪️ Assess incisor inclination before deciding whether a Class II or Class III relationship is primarily dental or skeletal.
▪️ Interpret ANB, Wits, and other cephalometric measurements as components of a diagnostic system, not isolated treatment determinants.
▪️ Evaluate the facial profile and vertical proportions before selecting orthodontic camouflage.
▪️ When dental compensation approaches its biological limits, orthognathic evaluation should be considered rather than forcing further tooth movement.
▪️ In surgical cases, presurgical decompensation is intended to expose and facilitate correction of the true skeletal discrepancy, not to improve the occlusion before surgery.

📚 References

✔ Alhammadi, M. S., Almashraqi, A. A., Khadhi, A. H., Arishi, K. A., Alamir, A. A., Beleges, E. M., & Halboub, E. (2022). Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: A systematic review. Clinical Oral Investigations, 26(11), 6443–6455. https://doi.org/10.1007/s00784-022-04685-6
✔ Benyaia, H., Azaroual, M. F., Garcia, C., Hamou, E., Abouqal, R., & Zaoui, F. (2011). Treatment of skeletal Class III malocclusions: Orthognathic surgery or orthodontic camouflage? How to decide. International Orthodontics, 9(2), 196–209. https://doi.org/10.1016/j.ortho.2011.03.005
✔ Raposo, R., Peleteiro, B., Paço, M., & Pinho, T. (2018). Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in Class II malocclusion: A systematic review and meta-analysis. International Journal of Oral and Maxillofacial Surgery, 47(4), 445–455. https://doi.org/10.1016/j.ijom.2017.09.003
✔ Sailer, H. F., & Prantl, F. A. (1999). Soft tissue cephalometric analysis: Diagnosis and treatment planning of dentofacial deformity. American Journal of Orthodontics and Dentofacial Orthopedics, 115(2), 224–232. https://doi.org/10.1016/S0889-5406(99)70345-8
✔ Sabri, R. (2006). Orthodontic objectives in orthognathic surgery: State of the art today. World Journal of Orthodontics, 7(2), 177–191.
✔ Stellzig-Eisenhauer, A., Lux, C. J., & Schuster, G. (2002). Treatment decision in adult patients with Class III malocclusion: Orthodontic camouflage versus orthognathic surgery. Journal of Orofacial Orthopedics, 63, 107–120.
✔ The British Association of Oral and Maxillofacial Surgeons. (2025). What are the limits of orthodontic treatment before surgical intervention is required? British Journal of Oral and Maxillofacial Surgery. https://doi.org/10.1016/j.bjoms.2025.07.008

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Minimally Invasive Pulpotomy in Symptomatic Teeth: Is It Possible?

Minimally Invasive Pulpotomy

Vital pulp therapy (VPT) has undergone a significant change in recent years. Historically, teeth with symptoms traditionally diagnosed as irreversible pulpitis were generally treated with root canal treatment or extraction.

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Current evidence indicates that selected mature permanent teeth with symptomatic pulpitis may retain sufficient reparative potential to be managed with pulpotomy.

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However, minimally invasive pulpotomy should not be regarded as a single standardized technique. The term is better understood as a tissue-preserving therapeutic approach in which the amount of pulp removed is limited to the tissue considered clinically compromised, while maintaining the vitality of the remaining pulp.
This distinction is important because Cvek partial pulpotomy represents a specific historical technique for partial removal of exposed coronal pulp, particularly in traumatic pulp exposures, whereas contemporary pulpotomy protocols have expanded into the management of cariously exposed mature permanent teeth with symptoms indicative of irreversible pulpitis.

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What Is Minimally Invasive Pulpotomy?
A minimally invasive approach to pulpotomy aims to preserve the maximum amount of viable pulp compatible with effective removal of inflamed tissue and achievement of hemostasis.
The amount of tissue removed is therefore not determined exclusively by a predefined depth. Instead, it may be adjusted according to the clinical condition of the pulp after exposure.
Three concepts should be distinguished:
Procedure Main Characteristic Typical Clinical Context
Cvek partial pulpotomy Limited removal of superficial exposed pulp, historically involving approximately 1–2 mm of tissue. Traumatic pulp exposure, particularly in permanent incisors.
Contemporary partial pulpotomy Removal of a limited amount of coronal pulp according to tissue condition and the ability to achieve hemostasis. Selected carious pulp exposures, including mature teeth with symptomatic pulpitis.
Full pulpotomy Removal of the entire coronal pulp to the level of the canal orifices while preserving the radicular pulp. Mature teeth in which more extensive coronal pulp removal is required.
The Cvek technique should therefore not be used synonymously with minimally invasive pulpotomy. Its historical evidence base is primarily associated with traumatic pulp exposures, whereas contemporary partial pulpotomy has been investigated in mature permanent teeth with carious exposure and symptomatic pulpitis.

Can Symptomatic Teeth Be Treated With a Minimally Invasive Approach?
Yes, in selected cases.
The current evidence challenges the assumption that symptoms traditionally associated with irreversible pulpitis automatically indicate complete loss of pulpal healing potential. The AAE recognizes that VPT may be considered in appropriately selected mature teeth previously diagnosed with irreversible pulpitis and emphasizes direct assessment of the exposed pulp as an important component of case selection.
A 2024 systematic review and meta-analysis found favorable outcomes for pulpotomy in mature permanent teeth diagnosed with irreversible pulpitis, although the authors emphasized limitations in the available evidence and heterogeneity among studies.
Importantly, the evidence does not mean that every symptomatic tooth is a candidate for partial pulpotomy. Rather, pulpal status must be reassessed after exposure and tissue removal.

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Partial Pulpotomy in Symptomatic Mature Teeth
Contemporary randomized clinical trials provide increasing evidence supporting partial pulpotomy in selected mature permanent teeth with symptoms indicative of irreversible pulpitis.
In a randomized trial involving 50 mature molars, partial pulpotomy using Biodentine achieved an 88% success rate at 12 months, compared with 91.6% for full pulpotomy, with no statistically significant difference between groups.
Another randomized trial involving 106 mature mandibular molars reported 80.8% success for partial pulpotomy and 89.8% for complete pulpotomy at 12 months. Although the numerical difference favored complete pulpotomy, it was not statistically significant. The authors concluded that partial pulpotomy may be attempted because of its more conservative nature.
More recent research has also investigated how much pulp should be removed during partial pulpotomy. A 2025 randomized clinical trial compared restricted partial pulpotomy, in which approximately 2–3 mm of superficial pulp was removed only at the exposure site, with an extended approach involving removal of 2–3 mm of superficial pulp throughout the pulp chamber. This reflects the continuing shift toward determining the extent of tissue removal according to biological rather than purely mechanical criteria.

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Clinical Determinants of Success
The key issue is not simply how little pulp can be removed, but whether the remaining pulp is capable of healing.
Clinical Factor Importance in Treatment Selection
Preoperative diagnosis Establishes the initial pulpal and periapical diagnosis but cannot determine the exact histological extent of inflammation.
Direct pulp assessment Provides additional information after pulp exposure and removal of clinically compromised tissue.
Hemostasis Controlled bleeding after pulp amputation supports proceeding with vital pulp therapy; persistent bleeding requires reassessment.
Aseptic isolation Reduces microbial contamination of the exposed pulp and treatment field.
Extent of inflammation Helps determine whether a limited partial pulpotomy or more extensive coronal pulp removal is appropriate.
Biomaterial Calcium silicate-based hydraulic cements are widely used in contemporary vital pulp therapy.
Coronal seal An effective definitive restoration is essential to prevent bacterial leakage and protect the treated pulp.
In randomized clinical studies, inability to control bleeding within a predefined period has been used as a criterion for abandoning the planned pulpotomy protocol. For example, one trial required hemostasis within six minutes before proceeding with treatment.
However, hemostasis time should not be interpreted as an absolute biological threshold. It is a clinical decision aid rather than a direct histological measurement of pulpal inflammation.

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A Contemporary Minimally Invasive Protocol
A tissue-preserving approach should follow a biologically guided sequence:

1. Establish the pulpal and periapical diagnosis.
2. Obtain appropriate preoperative radiographs.
3. Achieve rubber dam isolation and aseptic control.
4. Remove infected dentin and expose the pulp when indicated.
5. Remove the clinically compromised coronal pulp.
6. Assess the remaining tissue and establish hemostasis.
7. Determine whether partial or full pulpotomy provides the most appropriate level of tissue removal.
8. Apply an appropriate calcium silicate-based biomaterial.
9. Provide a durable definitive coronal restoration.
10. Perform clinical and radiographic follow-up.
This approach is consistent with the contemporary VPT concept that direct visualization of pulp tissue after exposure can contribute to treatment selection, because conventional sensibility testing cannot establish the histological status of the pulp with sufficient precision.

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Is the Cvek Technique the Same Procedure?
No.
The Cvek partial pulpotomy is a specific form of partial pulpotomy historically associated with traumatic crown fractures and exposed vital pulp, particularly in permanent incisors. The classic procedure involved removal of a small superficial portion of exposed pulp followed by placement of a pulp-capping material.
Long-term clinical studies have demonstrated favorable outcomes for partial pulpotomy in traumatized permanent incisors.
Contemporary partial pulpotomy for symptomatic carious teeth is conceptually related because both procedures preserve vital pulp tissue. However, they should not be treated as identical techniques because their indications, clinical circumstances, and evidence bases differ.

Thus:
Cvek partial pulpotomy = a specific partial pulpotomy technique.
Minimally invasive pulpotomy = a broader tissue-preservation approach that may involve partial or, when clinically necessary, full pulpotomy.

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💬 Discussion
The most important change in contemporary VPT is not the introduction of a new pulpotomy technique, but the recognition that pulpal inflammation is biologically heterogeneous. Clinical symptoms alone cannot reliably determine whether all remaining pulp tissue has lost its capacity for healing.
Consequently, a diagnosis such as symptomatic irreversible pulpitis should not automatically be interpreted as evidence that every portion of the pulp is irreversibly damaged. The AAE and contemporary evidence support combining preoperative diagnosis with direct intraoperative assessment when VPT is being considered.
The evidence supporting partial pulpotomy is particularly relevant to the minimally invasive concept. Randomized trials have demonstrated favorable short-term outcomes and, in several studies, no statistically significant difference between partial and full pulpotomy.
Nevertheless, the current evidence does not justify assuming that partial pulpotomy is universally superior. Some studies report numerically higher success with full pulpotomy, while follow-up periods remain relatively short in much of the literature. A 2024 meta-analysis likewise concluded that the evidence is promising but affected by heterogeneity and methodological limitations.
Therefore, the objective of minimally invasive pulpotomy should not be “remove as little pulp as possible”. The biologically appropriate objective is to remove compromised tissue while preserving the greatest amount of healthy, functional pulp that can predictably remain viable.

✍️ Conclusion
Minimally invasive pulpotomy is a valid contemporary concept within vital pulp therapy, but it is not synonymous with the Cvek technique.
The Cvek procedure is a specific form of partial pulpotomy historically used for traumatic pulp exposures. Contemporary minimally invasive pulpotomy encompasses a broader tissue-preserving philosophy that may involve partial or full pulpotomy according to the clinical condition of the pulp.
In selected mature permanent teeth with symptoms indicative of irreversible pulpitis, current evidence supports pulpotomy as a potential alternative to root canal treatment. However, successful treatment depends on appropriate case selection, asepsis, direct pulp assessment, effective hemostasis, suitable biomaterials, and a reliable coronal seal.

🎯 Clinical Recommendations
▪️ Do not use Cvek partial pulpotomy and minimally invasive pulpotomy as interchangeable terms.
▪️ Consider contemporary partial pulpotomy in selected symptomatic mature teeth when the remaining pulp demonstrates favorable clinical characteristics after tissue removal.
▪️ Do not impose a predetermined depth of tissue removal when the clinical condition of the pulp indicates that additional removal is necessary.
▪️ Use hemostasis and direct pulp assessment as important intraoperative decision points rather than relying exclusively on the preoperative diagnosis.
▪️ If a limited partial pulpotomy does not provide a suitable pulpal wound or controlled hemostasis, progress to a more extensive pulpotomy or reconsider VPT, according to the clinical circumstances.
▪️ Consider long-term follow-up essential because short-term symptom resolution does not by itself demonstrate sustained pulp vitality.

📚 References

✔ American Association of Endodontists. (2021). AAE position statement on vital pulp therapy. American Association of Endodontists.
✔ Duncan, H. F., Kirkevang, L.-L., Peters, O. A., El-Karim, I., Krastl, G., Del Fabbro, M., Chong, B. S., Galler, K. M., Segura-Egea, J. J., & Kebschull, M. (2023). Treatment of pulpal and apical disease: The European Society of Endodontology S3-level clinical practice guideline. International Endodontic Journal, 56(Suppl. 3), 238–295. https://doi.org/10.1111/iej.13974
✔ Jassal, A., Nawal, R. R., Yadav, S., Talwar, S., Yadav, S., & Duncan, H. F. (2023). Outcome of partial and full pulpotomy in cariously exposed mature molars with symptoms indicative of irreversible pulpitis: A randomized controlled trial. International Endodontic Journal, 56(3), 331–344. https://doi.org/10.1111/iej.13872
✔ Li, Y., Wang, W., Zeng, Q., Tang, M., Massey, J., Bergeron, B. E., Gu, L., & Tay, F. R. (2024). Efficacy of pulpotomy in managing irreversible pulpitis in mature permanent teeth: A systematic review and meta-analysis. Journal of Dentistry, 144, 104923. https://doi.org/10.1016/j.jdent.2024.104923
✔ Ramani, A., Sangwan, P., Tewari, S., Duhan, J., Mittal, S., & Kumar, V. (2022). Comparative evaluation of complete and partial pulpotomy in mature permanent teeth with symptomatic irreversible pulpitis: A randomized clinical trial. International Endodontic Journal, 55(5), 430–440. https://doi.org/10.1111/iej.13714
✔ Ramani, A., Sangwan, P., Tewari, S., Duhan, J., Mittal, S., & Kumar, V. (2025). Effect of lateral extent of pulp tissue removal on the outcome of partial pulpotomy for managing cariously exposed mature permanent molars with symptomatic irreversible pulpitis: A randomized clinical trial. International Endodontic Journal, 58(1), 71–83. https://doi.org/10.1111/iej.14152
✔ Tzanetakis, G. N., Koletsi, D., & Georgopoulou, M. (2023). Treatment outcome of partial pulpotomy using two different calcium silicate materials in mature permanent teeth with symptoms of irreversible pulpitis: A randomized clinical trial. International Endodontic Journal, 56(10), 1178–1196. https://doi.org/10.1111/iej.13955

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How Diabetes Increases the Risk of Oral Infections

Diabetes - Oral infections

Diabetes mellitus can substantially modify the oral environment and increase susceptibility to several oral infections and inflammatory diseases, particularly when glycemic control is poor.

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Hyperglycemia affects immune function, vascular physiology, inflammatory signaling, salivary function, and tissue repair, creating conditions that may facilitate microbial dysbiosis and prolong inflammation.

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The strongest evidence concerns the relationship between diabetes and periodontitis, which is now recognized as bidirectional. Contemporary longitudinal evidence also supports an association between diabetes and subsequent periodontal disease, although the magnitude of this association varies among studies.

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How Does Diabetes Increase the Risk of Oral Infections?
Several biological mechanisms contribute to increased susceptibility.

1. Impaired Host Immune Response
Persistent hyperglycemia can alter innate immune-cell function, including neutrophil chemotaxis, adhesion, and phagocytic activity. This may reduce the efficiency with which the host controls pathogenic microorganisms within the oral biofilm.
At the same time, diabetes can promote a disproportionate inflammatory response to microbial challenge. The resulting imbalance between microbial control and inflammation is particularly important in periodontal tissues.

2. Hyperglycemia, AGEs, and Chronic Inflammation
Chronic hyperglycemia promotes the formation and accumulation of advanced glycation end products (AGEs). Interaction between AGEs and their receptor, RAGE, can increase oxidative stress and pro-inflammatory signaling.
In periodontal tissues, these mechanisms amplify the inflammatory response to the subgingival biofilm and contribute to connective-tissue and alveolar bone destruction.

3. Altered Salivary Function
Diabetes may be associated with reduced salivary flow, lower salivary pH, and reduced buffering capacity. A 2024 systematic review and meta-analysis found significant reductions in these salivary parameters among adults with type 2 diabetes, together with a higher DMFT index compared with non-diabetic individuals.
Reduced salivary protection can facilitate dental caries, particularly when combined with dietary factors, inadequate plaque control, or other xerogenic conditions.

4. Increased Periodontal Susceptibility
Periodontitis is the oral condition most consistently associated with diabetes. Diabetes is considered an important modifying factor for periodontal disease, and poor glycemic control is associated with greater periodontal severity and progression.
The relationship is bidirectional: periodontal inflammation can contribute to systemic inflammatory burden and adversely affect glycemic control. A 2026 systematic review and meta-analysis of 28 longitudinal studies involving more than 300,000 participants found evidence of temporal associations in both directions between diabetes and periodontitis.

5. Oral Candidiasis and Other Opportunistic Conditions
Oral candidiasis has been associated with diabetes, particularly in the presence of poor glycemic control, xerostomia, denture use, or other local risk factors. However, the strength of evidence is not equivalent to that observed for periodontitis.
A systematic review and meta-analysis found no statistically significant overall increase in oral candidiasis among diabetic patients, although denture stomatitis was more common in diabetic individuals. The certainty of this evidence was considered very low.
Therefore, diabetes should be considered a predisposing or modifying factor, rather than an independent explanation for every oral fungal infection.

Main Oral Conditions Associated With Diabetes
Oral condition Relationship with diabetes Relevant mechanisms
Periodontitis Strong and well-established association Immune dysregulation, hyperglycemia, AGEs/RAGE, oxidative stress, exaggerated inflammation
Dental caries Increased risk may occur, particularly in some diabetic populations Reduced salivary flow, lower pH and buffering capacity, dietary and plaque-related factors
Oral candidiasis Possible association; evidence is less consistent Altered host defense, hyperglycemia, xerostomia and local factors
Denture stomatitis Higher risk reported in diabetic patients Candida-related biofilm, denture factors and altered host response
Clinical Assessment
For dental professionals, glycemic control should be considered when assessing infection risk and treatment prognosis. A comprehensive history should include diabetes type, current medications, recent glycemic status when available, diabetes-related complications, and previous episodes of hypoglycemia or poor healing.
The American Diabetes Association Standards of Care 2026 recommends at least annual dental examination for people with diabetes and emphasizes coordination between medical and dental teams. Dental assessment should include periodontal evaluation and consideration of oral complications associated with diabetes.

Clinicians should pay particular attention to:
▪️ Bleeding on probing, periodontal pocketing, attachment loss, and tooth mobility
▪️ Recurrent or persistent oral infections
▪️ Xerostomia or symptoms suggesting salivary hypofunction
▪️ Root and coronal caries
▪️ Oral candidiasis and denture-associated inflammation
▪️ Delayed healing after invasive procedures
▪️ Evidence of inadequate glycemic control when clinically relevant

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💬 Discussion
The increased risk of oral disease in diabetes is not explained simply by the presence of elevated glucose in the oral cavity. Rather, hyperglycemia modifies the host–microbiome interaction, alters immune and inflammatory responses, and may compromise salivary protection and tissue repair.
Among oral conditions, periodontitis has the strongest and most clinically relevant evidence base. The association is also bidirectional: diabetes increases periodontal susceptibility, while periodontal inflammation may adversely influence glycemic control. The 2018 EFP/IDF consensus reported that periodontal therapy is safe in patients with diabetes and may produce modest reductions in HbA1c, although the long-term metabolic effect remains less certain.
Evidence for caries and salivary dysfunction has strengthened in recent years, with 2024 meta-analytic data demonstrating altered salivary parameters and higher caries experience in adults with type 2 diabetes. In contrast, evidence regarding oral candidiasis is less consistent and should be interpreted in the context of additional local and systemic risk factors.
Consequently, oral infection prevention should be incorporated into diabetes care rather than treated as an isolated dental issue.

✍️ Conclusion
Diabetes increases susceptibility to oral disease primarily through altered immune function, chronic inflammation, hyperglycemia-related tissue changes, salivary dysfunction, and impaired healing. The most firmly established association is with periodontitis, but caries, xerostomia-related complications, and selected fungal conditions may also be clinically relevant.
Effective management requires glycemic control, periodontal prevention and treatment, individualized caries prevention, appropriate oral hygiene, and coordination between dental and medical professionals.

🎯 Clinical Recommendations
1. Perform at least an annual comprehensive dental and periodontal examination in patients with diabetes, with shorter recall intervals when periodontal disease or other risk factors are present.
2. Consider glycemic status when evaluating periodontal prognosis, infection recurrence, and healing, particularly in patients with poorly controlled diabetes.
3. Prioritize periodontal prevention and treatment, because periodontitis represents the most consistently established oral complication associated with diabetes.
4. Assess salivary function and caries risk when xerostomia, recurrent caries, or root-surface lesions are present.
5. Investigate recurrent candidiasis or denture stomatitis for additional predisposing factors, rather than attributing the condition exclusively to diabetes.
6. Coordinate dental and medical care when glycemic control is inadequate or invasive treatment requires consideration of the patient's diabetes medications and hypoglycemia risk.

📚 References

✔ Botelho, J., Singh, S., Varenne, B., Rendell, N., Harada, Y., Proença, L., Machado, V., & Bitencourt, F. V. (2026). Oral health and diabetes: A systematic review and meta-analysis. The Lancet Public Health, 11(8), e555–e566. https://doi.org/10.1016/S2468-2667(26)00149-0
✔ Chapple, I. L. C., & Genco, R. (2013). Diabetes and periodontal diseases: Consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases. Journal of Clinical Periodontology, 40(Suppl. 14), S106–S112. https://doi.org/10.1111/jcpe.12077
✔ Martorano-Fernandes, L., Dornelas-Filho, A. P., de Faria, R. L., & others. (2020). Oral candidiasis and denture stomatitis in diabetic patients: Systematic review and meta-analysis. Brazilian Oral Research, 34, e113. https://doi.org/10.1590/1807-3107bor-2020.vol34.0113
✔ Sanz, M., Ceriello, A., Buysschaert, M., Chapple, I., Demmer, R. T., Graziani, F., Herrera, D., Jepsen, S., Lione, L., Madianos, P., Mathur, M., Montanya, E., Shapira, L., Tonetti, M., & Vegh, D. (2018). Scientific evidence on the links between periodontal diseases and diabetes: Consensus report and guidelines of the joint workshop on periodontal diseases and diabetes by the International Diabetes Federation and the European Federation of Periodontology. Journal of Clinical Periodontology, 45(2), 138–149. https://doi.org/10.1111/jcpe.12808
✔ Zhou, G., Shu, X., Long, Y., Cao, Y., Wang, J., Liao, G., & Zou, L. (2024). Dental caries and salivary alterations in patients with type 2 diabetes: A systematic review and meta-analysis. Journal of Dentistry, 150, 105321. https://doi.org/10.1016/j.jdent.2024.105321

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martes, 8 de septiembre de 2026

Clinical Applications of Cinch Back Mechanics

Cinch Back Mechanics

Cinch back mechanics refers to the controlled distal bending of an orthodontic archwire beyond the molar tube to restrict unwanted archwire displacement.

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Although commonly considered a method of securing the distal wire end, its clinical importance extends to force-system control, particularly during intrusion and other mechanics in which anterior archwire movement can influence incisor inclination.

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The clinical effect of a cinch back depends on the archwire, activation, anchorage system, and initial dental relationships. Therefore, its application should be based on the intended biomechanical objective rather than used routinely in every orthodontic case.

1. Incisor Intrusion and Overbite Correction
One of the most clinically relevant applications is incisor intrusion in deep-bite treatment.
When an intrusion arch is not cinched back, the archwire can move through the molar tube as the anterior segment responds to the applied force. This may permit unwanted labial tipping and proclination of the incisors.
A randomized clinical trial involving 44 patients treated with a Connecticut intrusion arch found a significant difference in maxillary incisor inclination according to the presence of a cinch back. Without a cinch back, the incisors showed approximately 2.17° of labial flaring and 1.68 mm of proclination. With a cinch back, the incisors demonstrated approximately 1.99° of palatal inclination and 1.13 mm of retroclination. Importantly, the amount of incisor intrusion itself was not significantly different between groups.
This finding indicates that the cinch back primarily modifies the anteroposterior and angular response of the incisors, rather than necessarily increasing the amount of intrusion.

2. Control of Incisor Proclination
The cinch back may be particularly useful when further labial movement of the incisors is undesirable.

This consideration is clinically important in patients presenting with:
▪️ Pre-existing incisor proclination
▪️ Increased overjet
▪️ Thin anterior alveolar housing
▪️ A treatment objective requiring controlled incisor inclination
▪️ Deep bite requiring intrusion without additional labial displacement
Recent clinical research continues to identify uncontrolled incisor proclination as an important consideration during intrusion mechanics because excessive labial movement may be associated with unfavorable periodontal and alveolar bone changes.
However, the appropriate response depends on the initial incisor position. A cinch back should not automatically be considered advantageous when incisor proclination is actually part of the treatment objective.

3. Utility and Intrusion Arches
Utility arches and intrusion arches are commonly used with a distal cinch back to limit anterior wire displacement.
In mandibular incisor intrusion, for example, a cinch back can be incorporated after the archwire is engaged in the anterior brackets. Recent randomized clinical research describing utility-arch mechanics specifically used a distal bend beyond the molar tube to prevent forward wire slippage and the associated tendency toward incisor flaring.
The clinical objective is therefore not simply to retain the wire but to maintain a more controlled relationship between the posterior anchorage unit and the anterior segment.

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4. Reverse-Curve and Deep-Bite Mechanics
The cinch back can also be incorporated into reverse-curve archwire mechanics when control of anterior wire displacement is required.

However, the resulting tooth movement should be interpreted as the combined effect of:
▪️ Archwire curvature
▪️ Wire stiffness
▪️ Bracket engagement
▪️ Anchorage
▪️ Force magnitude
▪️ Moments generated by the appliance
▪️ Initial incisor inclination
Therefore, the cinch back should be regarded as one component of a larger biomechanical system, rather than as an isolated method for correcting deep bite.

5. Anchorage and Posterior Effects
Although the primary clinical objective may involve the incisors, cinch back mechanics can also influence the posterior segment.
In the Connecticut intrusion-arch trial, the cinched-back group demonstrated distal tipping of the maxillary first molars, although the difference in molar positional changes between groups was not statistically significant for the principal measurements.
This is clinically relevant because restricting archwire movement can alter the distribution of the reciprocal forces and moments between anterior and posterior segments.
Consequently, anchorage should be evaluated before activating an intrusion system with a cinch back, particularly when posterior tooth movement would be undesirable.

6. Cinch Back With Nickel-Titanium Archwires
Application of a cinch back to NiTi archwires presents a technical limitation because conventional NiTi is difficult to bend permanently.
Localized annealing has been described to facilitate distal bending. However, uncontrolled heating can alter the mechanical properties of NiTi. A published technique specifically addressed the need to control the annealed portion of the archwire because excessive heating may compromise the desired properties of the untreated segment.
Therefore, distal cinching of NiTi should be performed with appropriate control of the wire's thermal and mechanical properties rather than by indiscriminate heating.

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🔹 Clinical Application by Treatment Objective
Treatment Objective Potential Role of Cinch Back
Incisor intrusion Limit anterior archwire displacement and modify incisor tipping.
Control of proclination Reduce unwanted labial movement during intrusion mechanics.
Utility arch mechanics Restrict forward wire slippage during anterior activation.
Reverse-curve mechanics Help maintain the intended position of the active archwire.
Archwire stabilization Restrict longitudinal wire movement within the molar tube.
💬 Discussion
The clinical significance of cinch back mechanics lies in their ability to modify how an active archwire expresses its force system. The strongest direct clinical evidence comes from intrusion mechanics, where the presence or absence of the distal bend produced significantly different effects on maxillary incisor inclination and anteroposterior displacement.
Importantly, the evidence does not support interpreting cinch back as a universal method for increasing intrusion. In the prospective clinical trial, both cinched and non-cinched groups achieved comparable amounts of incisor intrusion, while the principal difference was the direction of incisor tipping.
This distinction has practical importance. The decision to cinch should be determined by the desired incisor movement, the existing sagittal position of the incisors, and the anchorage requirements of the case.
Evidence regarding other applications, including routine archwire stabilization and reverse-curve mechanics, is more heterogeneous. These applications are supported by biomechanical principles and clinical studies, but the evidence base is not as strong as that available for the specific relationship between cinch back and incisor response during intrusion.

🎯 Clinical Recommendations
▪️ Assess initial incisor inclination before cinching. A cinch back is particularly relevant when additional labial tipping is undesirable.
▪️ During incisor intrusion, distinguish between the desired amount of intrusion and the desired incisor inclination; the cinch back primarily influences the latter.
▪️ Evaluate posterior anchorage, because restricting archwire movement can alter the reciprocal force system.
▪️ Avoid treating the cinch back as an automatic component of every reverse-curve or intrusion arch; its indication should follow the intended biomechanics.
▪️ When using NiTi archwires, use controlled methods for creating a distal bend and avoid excessive heating that could alter the wire's mechanical properties.

✍️ Conclusion
Cinch back mechanics provide a simple method for controlling distal archwire movement, but their clinical effects extend into the biomechanics of active orthodontic treatment. Their most clearly demonstrated application is during incisor intrusion, where a distal bend can reduce unwanted incisor proclination and alter the direction of incisor tipping without necessarily increasing the amount of intrusion.
The clinical decision to use a cinch back should therefore be based on initial tooth position, treatment objectives, anchorage requirements, and the specific force system generated by the archwire.

📚 References

✔ Schwertner, A., de Almeida, R. R., de Almeida-Pedrin, R. R., Fernandes, T. M. F., Oltramari, P., & de Almeida, M. R. (2020). A prospective clinical trial of the effects produced by the Connecticut intrusion arch on the maxillary dental arch. The Angle Orthodontist, 90(4), 500–506. https://doi.org/10.2319/102219-666.1
✔ Patil, H. A., Chitko, S. S., Kerudi, V. V., Patil, N. S., & Tekale, P. D. (2015). Economical, efficient, simple device for controlled annealing NiTi archwire. Journal of Clinical and Diagnostic Research, 9(8), ZH01–ZH02. https://doi.org/10.7860/JCDR/2015/13668.6362
✔ Janakiraman, N., et al. (2016). Response of the maxillary dentition to a statically determinate one-couple system with tip-back mechanics: A prospective clinical trial. The Angle Orthodontist, 86(1), 105–111. https://doi.org/10.2319/012815-68.1
✔ Zhang, N., & Liu, X. (2012). Three dimensional changes of lower teeth with NiTi round or square rocking chair archwire. Chinese Journal of Stomatology, 47(3), 169–173.

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lunes, 7 de septiembre de 2026

Updated Treatments for Gummy Smile: What Works Today

Gummy Smile

Excessive gingival display (EGD), commonly referred to as a gummy smile, is a multifactorial esthetic condition in which an excessive amount of maxillary gingiva is visible during smiling.

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Although gingival exposure of approximately 1–2 mm may be considered within an esthetically acceptable range, the clinical significance of EGD depends on facial proportions, lip dynamics, tooth dimensions, gingival architecture, and patient perception.

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Current management emphasizes etiologic diagnosis rather than a single universal treatment. Altered passive eruption, dentoalveolar extrusion, vertical maxillary excess, gingival enlargement, short or hypermobile upper lip, and combinations of these factors may coexist.
Therefore, treatment selection should be based on a comprehensive periodontal, dental, orthodontic, and facial assessment.

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Diagnosis Before Treatment
A predictable treatment plan begins with identifying the principal source of gingival exposure. Clinical evaluation should include:

▪️ Gingival display during posed and maximum smile.
▪️ Upper lip length and mobility.
▪️ Maxillary incisor display at rest and during smiling.
▪️ Clinical crown dimensions and tooth proportions.
▪️ Periodontal probing and assessment of the cementoenamel junction.
▪️ Incisor inclination and vertical position.
▪️ Occlusal relationships and overbite.
▪️ Facial proportions and lower anterior facial height.
▪️ Cephalometric assessment when vertical maxillary excess is suspected.
This diagnostic process is particularly important because treating only one component of a multifactorial gummy smile may produce an incomplete or unstable esthetic result.

Updated Treatment Options for Gummy Smile
Etiologic Factor Preferred Treatment Approach Main Clinical Objective
Altered passive eruption Esthetic crown lengthening ± osseous recontouring Increase clinical crown exposure
Dentoalveolar extrusion Orthodontic intrusion, frequently with TAD-supported anchorage Reposition the incisors apically
Hypermobile upper lip Lip repositioning or botulinum toxin type A Reduce excessive upper-lip elevation
Vertical maxillary excess Orthognathic surgery Correct the underlying skeletal discrepancy
Gingival enlargement Periodontal therapy, gingivectomy, or appropriate surgical correction Reduce excessive gingival tissue
Multifactorial EGD Multidisciplinary treatment Address dental, periodontal, skeletal, and muscular components
1. Esthetic Crown Lengthening
Esthetic crown lengthening is particularly appropriate when excessive gingival display results from altered passive eruption or excessive gingival coverage of otherwise adequately proportioned teeth.
The procedure may involve gingivectomy alone or, when necessary, apical repositioning with osseous recontouring to establish an appropriate supracrestal tissue relationship. The American Academy of Periodontology recognizes crown lengthening as an approach for exposing additional tooth structure when excessive gingival tissue makes the teeth appear short.
Importantly, crown lengthening should not be used to compensate for a skeletal or muscular etiology.

2. Orthodontic Intrusion
When EGD is associated with maxillary incisor or anterior dentoalveolar extrusion, orthodontic intrusion can reduce gingival exposure while preserving the periodontal architecture.
Temporary anchorage devices (TADs) have expanded the clinician's ability to achieve controlled anterior intrusion while minimizing unwanted posterior movement. Recent evidence suggests that TAD-supported mechanics can provide favorable intrusion outcomes, although the certainty of evidence remains limited and treatment protocols vary.
This approach is especially relevant when EGD is accompanied by deep overbite, excessive incisor display, or an unfavorable vertical incisor position.

3. Lip Repositioning
Lip repositioning surgery reduces the upward movement of the upper lip by limiting vestibular muscle excursion. It is most appropriate when upper-lip hypermobility is a major contributor and there is no major skeletal discrepancy requiring orthognathic correction.
A systematic review and meta-analysis reported an overall reduction in gingival display of approximately 3 mm at 6 months, with reductions remaining measurable at 12 and 36 months. Some modified techniques, particularly those incorporating periosteal suturing, demonstrated greater reductions.
However, patient selection remains important because recurrence or partial relapse can occur, particularly during the early postoperative period.

4. Botulinum Toxin Type A
Botulinum toxin type A (BTX-A) is a minimally invasive option for patients whose EGD is predominantly associated with hyperactivity of the upper-lip elevator muscles.
Systematic reviews and meta-analyses demonstrate a clinically relevant short-term reduction in gingival exposure. One meta-analysis reported an average reduction of approximately 3.4 mm at two weeks, with the effect progressively diminishing and tending to approach baseline by approximately 24 weeks.
Consequently, BTX-A should be regarded as a temporary treatment, rather than a definitive correction of skeletal or dental abnormalities. It can be particularly useful when the patient prefers a minimally invasive approach or when muscle hyperactivity is the dominant etiologic factor.

5. Orthognathic Surgery
When vertical maxillary excess is the principal cause of excessive gingival display, Le Fort I maxillary impaction or another appropriately planned orthognathic procedure may provide the most comprehensive correction.
Unlike treatments directed primarily at gingival tissue or lip dynamics, orthognathic surgery addresses the underlying skeletal discrepancy. Current evidence supports its role particularly in patients with significant vertical maxillary excess, although treatment involves substantially greater morbidity and requires multidisciplinary planning.

6. Multidisciplinary and Combined Treatment
Many patients do not have a single etiologic factor. For example, altered passive eruption may coexist with incisor extrusion and upper-lip hypermobility.
In such cases, combined treatment may provide a more predictable result than attempting to correct all gingival exposure through one procedure. Periodontal surgery, orthodontic intrusion, lip repositioning, BTX-A, or orthognathic surgery should therefore be considered according to the dominant etiologic components rather than simply the amount of gingiva displayed.

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Clinical Decision-Making
A practical treatment sequence is:
Diagnosis → Etiologic classification → Severity assessment → Identify dominant factor → Select the least invasive effective treatment → Evaluate residual EGD → Consider combined therapy when indicated.
The objective should not simply be to eliminate every millimeter of visible gingiva. Facial harmony, tooth–lip relationships, periodontal health, and patient expectations should determine the final treatment target.

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💬 Discussion
The contemporary management of gummy smile has shifted from procedure-driven correction toward etiology-driven treatment planning. The available evidence supports several effective interventions, but their indications differ substantially.
Crown lengthening is highly appropriate for altered passive eruption, whereas orthodontic intrusion addresses an unfavorable dentoalveolar position. Lip repositioning and BTX-A primarily target excessive lip elevation, while orthognathic surgery is indicated when the underlying problem is skeletal.
The evidence is strongest for the principle that accurate diagnosis is fundamental, while comparative evidence between many treatment modalities remains limited. Recent systematic reviews also emphasize heterogeneity in patient selection, treatment protocols, outcome measurements, and follow-up periods.
Therefore, treatment should be individualized rather than based exclusively on a numerical gingival-display threshold.

🎯 Clinical Recommendations
1. Determine the etiology before selecting the procedure.
2. Use esthetic crown lengthening when altered passive eruption is the primary cause.
3. Consider TAD-assisted orthodontic intrusion when excessive incisor vertical position contributes to EGD.
4. Reserve lip repositioning primarily for patients with clinically significant upper-lip hypermobility.
5. Consider BTX-A when muscle hyperactivity predominates and a temporary, minimally invasive correction is acceptable.
6. Evaluate orthognathic surgery when vertical maxillary excess is clinically significant.
7. In multifactorial cases, consider sequential or combined interdisciplinary treatment rather than overcorrecting a single component.

✍️ Conclusion
Updated gummy smile treatment is increasingly based on individualized etiologic diagnosis rather than a single corrective technique. Crown lengthening, orthodontic intrusion, lip repositioning, botulinum toxin, and orthognathic surgery each have specific indications and limitations.
The most predictable results are achieved when clinicians identify the relative contribution of the periodontal, dental, skeletal, and muscular components before treatment. For complex cases, interdisciplinary planning remains essential to achieve stable and proportionate smile esthetics.

📚 References

✔ Ahmad Amro, L., et al. (2026). Prevalence of different etiologies of excessive gingival display: Identifying diagnostic patterns. The Scientific World Journal.
✔ AlMaghlouth, B., AlMubarak, A., Almaghlouth, I., AlKhalifah, R., Alsadah, A., & Hassan, A. (2021). Orthodontic intrusion using temporary anchorage devices compared to other orthodontic intrusion methods: A systematic review. Clinical, Cosmetic and Investigational Dentistry, 13, 11–19. https://doi.org/10.2147/CCIDE.S283102
✔ Dym, H., & Pierre, R. (2020). Diagnosis and treatment approaches to a “gummy smile.” Dental Clinics of North America, 64(2), 341–349. https://doi.org/10.1016/j.cden.2019.12.003
✔ Mendoza-Geng, A., Gonzales-Medina, K., Meza-Mauricio, J., Muniz, F. W. M. G., & Vergara-Buenaventura, A. (2022). Clinical efficacy of lip repositioning technique and its modifications for the treatment of gummy smile: Systematic review and meta-analysis. Clinical Oral Investigations, 26(6), 4243–4261. https://doi.org/10.1007/s00784-022-04467-0
✔ Pavone, A. F., Ghassemian, M., & Verardi, S. (2016). Gummy smile and short tooth syndrome—Part 1: Etiopathogenesis, classification, and diagnostic guidelines. Compendium of Continuing Education in Dentistry, 37(2), 102–107.
Silberberg, N., Goldstein, M., & Smidt, A. (2009). Excessive gingival display—Etiology, diagnosis, and treatment modalities. Quintessence International, 40(10), 809–818.
✔ Tomaz, A. F. G., et al. (2020). Impact of orthognathic surgery on the treatment of gummy smile: An integrative review. Oral and Maxillofacial Surgery.
✔ Vilarinho, D. F., et al. (2023). Contemporary treatment techniques for excessive gingival display caused by altered passive eruption or lip hypermobility. Journal of Esthetic and Restorative Dentistry.

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